Oncologic outcomes after percutaneous ablation for colorectal liver metastases: An updated comprehensive review Review

   


Authors: Chlorogiannis, D. D.; Sotirchos, V. S.; Sofocleous, C. T.
Review Title: Oncologic outcomes after percutaneous ablation for colorectal liver metastases: An updated comprehensive review
Abstract: Colorectal cancer is a major cause of cancer-related mortality, with liver metastases occurring in over a third of patients, and is correlated with poor prognosis. Despite surgical resection being the primary treatment option, only about 20% of patients qualify for surgery. Current guidelines recommend thermal ablation either alone or combined with surgery to treat limited hepatic metastases, provided that all visible disease can be effectively eradicated. Several ablation modalities, including radiofrequency ablation, microwave ablation, cryoablation, irreversible electroporation and histotripsy, are part of the percutaneous ablation armamentarium. Thermal ablation, including radiofrequency, microwave ablation and cryoablation, can offer local tumor control rates comparable to limited resection for selected tumors that can be ablated with margins. This review aims to encapsulate the current clinical evidence regarding the efficacy and oncologic outcomes after percutaneous ablation for the treatment of colorectal liver metastatic disease. © 2024 by the authors.
Keywords: treatment outcome; liver neoplasms; colorectal cancer; pathology; colorectal neoplasms; colorectal tumor; liver tumor; ablation techniques; surgery; radiofrequency ablation; ablation therapy; liver metastases; tumor ablation; interventional oncology; irreversible electroporation; procedures; hepatic malignancy; locoregional therapy; humans; human; ablation margin; histotripsy
Journal Title: Medicina (Lithuania)
Volume: 60
Issue: 9
ISSN: 1010-660X
Publisher: MDPI  
Date Published: 2024-09-01
Start Page: 1536
Language: English
DOI: 10.3390/medicina60091536
PUBMED: 39336577
PROVIDER: scopus
PMCID: PMC11433672
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85205078619&doi=10.3390%2fmedicina60091536&partnerID=40&md5=e15fe5f177094bac11767ca43e7f89f4
Notes: Review -- Source: Scopus
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MSK Authors
  1. Constantinos T Sofocleous
    245 Sofocleous
  2. Vlasios S Sotirchos
    54 Sotirchos
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