Randomized clinical trials in hepatocellular carcinoma Journal Article
| Authors: | Yopp, A. C.; Jarnagin, W. R. |
| Article Title: | Randomized clinical trials in hepatocellular carcinoma |
| Abstract: | Hepatocellular carcinoma is among the most common solid tumors, ranking behind only lung and gastric for cancer-related deaths worldwide. Despite improved surveillance programs in many countries, most patients present with advanced-stage cancer and chronic hepatic dysfunction limiting the available treatment options. This article reviews the most pertinent randomized controlled trials with respect to surgical and adjuvant interventions that shape the current treatment algorithm for hepatocellular carcinoma. © 2010 Elsevier Inc. All rights reserved. |
| Keywords: | cancer survival; clinical trial; drug tolerability; review; cancer recurrence; hepatocellular carcinoma; sorafenib; cisplatin; doxorubicin; interferon; iodinated poppyseed oil; placebo; artificial embolism; chemoembolization; diarrhea; drug withdrawal; hypophosphatemia; liver cell carcinoma; liver transplantation; side effect; unspecified side effect; carcinoma, hepatocellular; liver neoplasms; drug targeting; cancer adjuvant therapy; antineoplastic agent; evidence-based medicine; cancer palliative therapy; controlled clinical trial; enzyme inhibition; randomized controlled trial; weight reduction; randomized controlled trials as topic; surgical approach; randomized controlled trials; alcohol; drug response; tamoxifen; liver resection; sepsis; octreotide; virus hepatitis; radiofrequency ablation; hand foot syndrome; management; partial hepatectomy; abdominal drainage; gelfoam; menatetrenone |
| Journal Title: | Surgical Oncology Clinics of North America |
| Volume: | 19 |
| Issue: | 1 |
| ISSN: | 1055-3207 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2010-01-01 |
| Start Page: | 151 |
| End Page: | 162 |
| Language: | English |
| DOI: | 10.1016/j.soc.2009.09.012 |
| PUBMED: | 19914564 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Export Date: 20 April 2011" - "CODEN: SOCAF" - "Source: Scopus" |
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