Authors: | Plusa, B.; Hadjantonakis, A. K. |
Article Title: | Embryonic stem cell identity grounded in the embryo |
Abstract: | Pluripotent embryonic stem cells (ESCs) can be derived from blastocyst-stage mouse embryos. However, the exact in vivo counterpart of ESCs has remained elusive. A combination of expression profiling and stem cell derivation identifies epiblast cells from late-stage blastocysts as the source, and functional equivalent, of ESCs. © 2014 Macmillan Publishers Limited. All rights reserved. |
Keywords: | review; nonhuman; gene expression profiling; embryo; embryonic stem cell; embryo development; cell renewal; cell lineage; cell specificity; extracellular matrix; pluripotent stem cell; preimplantation embryo; mouse embryo; blastocyst; inner cell mass; ectoderm; nidation; human; priority journal |
Journal Title: | Nature Cell Biology |
Volume: | 16 |
Issue: | 6 |
ISSN: | 1465-7392 |
Publisher: | Nature Publishing Group |
Date Published: | 2014-06-01 |
Start Page: | 502 |
End Page: | 504 |
Language: | English |
DOI: | 10.1038/ncb2984 |
PROVIDER: | scopus |
PUBMED: | 24875737 |
PMCID: | PMC4950676 |
DOI/URL: | |
Notes: | Nature Cell Biol. -- Export Date: 8 July 2014 -- CODEN: NCBIF -- Source: Scopus |