Embryonic stem cell identity grounded in the embryo Journal Article


Authors: Plusa, B.; Hadjantonakis, A. K.
Article Title: Embryonic stem cell identity grounded in the embryo
Abstract: Pluripotent embryonic stem cells (ESCs) can be derived from blastocyst-stage mouse embryos. However, the exact in vivo counterpart of ESCs has remained elusive. A combination of expression profiling and stem cell derivation identifies epiblast cells from late-stage blastocysts as the source, and functional equivalent, of ESCs. © 2014 Macmillan Publishers Limited. All rights reserved.
Keywords: review; nonhuman; gene expression profiling; embryo; embryonic stem cell; embryo development; cell renewal; cell lineage; cell specificity; extracellular matrix; pluripotent stem cell; preimplantation embryo; mouse embryo; blastocyst; inner cell mass; ectoderm; nidation; human; priority journal
Journal Title: Nature Cell Biology
Volume: 16
Issue: 6
ISSN: 1465-7392
Publisher: Nature Publishing Group  
Date Published: 2014-06-01
Start Page: 502
End Page: 504
Language: English
DOI: 10.1038/ncb2984
PROVIDER: scopus
PUBMED: 24875737
PMCID: PMC4950676
DOI/URL:
Notes: Nature Cell Biol. -- Export Date: 8 July 2014 -- CODEN: NCBIF -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors