Extramedullary disease in APL: A real phenomenon to contend with or not? Journal Article
| Authors: | Ganzel, C.; Douer, D. |
| Article Title: | Extramedullary disease in APL: A real phenomenon to contend with or not? |
| Abstract: | In the last 2 decades an increasing number of patients reported with extramedullary involvement among relapsed acute promyelocytic leukemia (APL) patients. Several investigators related this phenomenon to the relatively new treatment of all-trans-retinoic-acid (ATRA). In this review article we will examine what has been reported in the medical literature on extramedullary disease in APL: the common sites to be involved, the clinical risk factors to its development, the role of ATRA and arsenic tri-oxide and the recommended treatment. © 2014 Elsevier Ltd. All rights reserved. |
| Keywords: | acute promyelocytic leukemia; apl; cns relapse; extramedullary disease |
| Journal Title: | Best Practice and Research: Clinical Haematology |
| Volume: | 27 |
| Issue: | 1 |
| ISSN: | 1521-6926 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2014-03-01 |
| Start Page: | 63 |
| End Page: | 68 |
| Language: | English |
| DOI: | 10.1016/j.beha.2014.04.001 |
| PROVIDER: | scopus |
| PUBMED: | 24907018 |
| DOI/URL: | |
| Notes: | Best Pract. Res. Clin. Haematol. -- Export Date: 8 July 2014 -- CODEN: BPRCA -- Source: Scopus |
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