Retinoblastoma: Saving life with vision Journal Article
| Author: | Abramson, D. H. |
| Article Title: | Retinoblastoma: Saving life with vision |
| Abstract: | Retinoblastoma has gone from >95% mortality to >95% survival in the past 100 years. Once enucleation techniques were perfected, the majority of children survived, but without the eye (or vision in that eye). Over the past 100 years, progressively better techniques have been developed for salvaging vision without sacrificing patient survival. Presently, 99% of children treated at our center survive their cancer, >99% retain at least one eye, and >90% retain normal vision in at least one eye. The introduction of ophthalmic artery chemosurgery has been the most dramatic, non-radiation-based mode to maximally preserve vision. © 2014 by Annual Reviews. All rights reserved. |
| Keywords: | cancer chemotherapy; cancer survival; treatment outcome; survival rate; cancer risk; systemic therapy; skin manifestation; cancer radiotherapy; radiation dose; chemotherapy; topotecan; antineoplastic agent; carboplatin; radiation; melphalan; retinoblastoma; platinum; enucleation; ophthalmic artery; retina detachment; external beam radiotherapy; second cancer; radon; chemosurgery; cobalt 60; blindness; linear accelerator; laser coagulation; pediatrics; cryotherapy; radiation induced neoplasm; intra-arterial; radium; cobalt therapy; beta radiation; nitrous oxide; diathermy; ophthalmic artery chemosurgery; cancer; human; priority journal; article |
| Journal Title: | Annual Review of Medicine |
| Volume: | 65 |
| ISSN: | 0066-4219 |
| Publisher: | Annual Reviews |
| Date Published: | 2014-01-01 |
| Start Page: | 171 |
| End Page: | 184 |
| Language: | English |
| DOI: | 10.1146/annurev-med-061312-123455 |
| PROVIDER: | scopus |
| PUBMED: | 24422571 |
| DOI/URL: | |
| Notes: | Annu. Rev. Med. -- Export Date: 8 July 2014 -- CODEN: ARMCA -- Source: Scopus |
