Are cancers of the esophagus, gastroesophageal junction, and cardia one disease, two, or several? Journal Article
| Author: | Rusch, V. W. |
| Article Title: | Are cancers of the esophagus, gastroesophageal junction, and cardia one disease, two, or several? |
| Abstract: | Recent epidemiological shifts have led to controversy about the etiology and treatment of gastroesophageal (GE) junction adenocarcinomas. The Siewert classification conveniently describes the anatomical location of these tumors relative to the GE junction. However, available data suggest that there may be epidemiological, clinical, and molecular differences among GE junction adenocarcinomas, depending on whether they are predominantly esophageal or gastric in location. Much more investigation is required to confirm or refute these apparent differences, which can affect clinical treament. © 2004 Elsevier Inc. All rights reserved. |
| Keywords: | cancer chemotherapy; cancer surgery; surgical technique; review; cancer localization; cancer radiotherapy; cancer staging; antineoplastic agent; cancer diagnosis; neoplasm staging; adenocarcinoma; carcinogenesis; anatomy; cancer classification; molecular biology; stomach neoplasms; esophagus carcinoma; esophageal neoplasms; lower esophagus sphincter; esophagogastric junction; cardia; terminology; epidemiological data; humans; human; priority journal |
| Journal Title: | Seminars in Oncology |
| Volume: | 31 |
| Issue: | 4 |
| ISSN: | 0093-7754 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2004-08-01 |
| Start Page: | 444 |
| End Page: | 449 |
| Language: | English |
| DOI: | 10.1053/j.seminoncol.2004.04.023 |
| PROVIDER: | scopus |
| PUBMED: | 15297937 |
| DOI/URL: | |
| Notes: | Semin. Oncol. -- Cited By (since 1996):19 -- Export Date: 16 June 2014 -- CODEN: SOLGA -- Source: Scopus |
