Chorioretinal scar growth after 810-nanometer laser treatment for retinoblastoma Journal Article
| Authors: | Lee, T. C.; Lee, S. W.; Dinkin, M. J.; Ober, M. D.; Beaverson, K. L.; Abramson, D. H. |
| Article Title: | Chorioretinal scar growth after 810-nanometer laser treatment for retinoblastoma |
| Abstract: | Purpose To determine the extent of expansion of laser scars after single treatment with transpupillary thermotherapy (TTT) for retinoblastoma. Design We retrospectively reviewed medical records and RetCam (Massie Industries, Dublin, CA) digital fundus photographs of patients with retinoblastoma who received TTT by use of an 810-nm diode laser with large-spot indirect ophthalmoscope. Digital images were measured by use of RetCam software beginning immediately after treatment. Lesions were measured in both linear size and area by 2 observers. In addition, optic disc diameters were also measured for each image. Participants We identified 9 patients with hereditary retinoblastoma who were treated from 1997 to 2000. Main outcome measures Linear and area expansion of laser scars as a function of time. Results Fourteen tumors in 10 eyes were treated successfully with 1 session of TTT. Follow-up for all eyes was at least 16 months. Scars of 12 of the 14 lesions increased beyond their original borders (mean starting linear diameter, 2.02 mm; range 1.46-2.59 mm; mean increase, 0.72 mm [36%]) over time, most within 6 months to 1 year after treatment. Conclusions Scars from TTT for retinoblastoma may increase in size after treatment. This expansion must be considered when applying TTT to tumors near vital macular structures, such as the fovea and optic nerve. © 2004 by the American Academy of Ophthalmology. |
| Keywords: | clinical article; controlled study; retrospective studies; review; follow up; follow-up studies; retinoblastoma; retinal neoplasms; postoperative complications; infant; infant, newborn; newborn; medical record; hyperthermic therapy; genetic disorder; hyperthermia, induced; retinal diseases; laser coagulation; scar; eye photography; cicatrix; eye fundus; diode laser; ophthalmoscope; chorioretinopathy; humans; human; male; female; priority journal; pupil; chorioretinal scar; choroid diseases |
| Journal Title: | Ophthalmology |
| Volume: | 111 |
| Issue: | 5 |
| ISSN: | 0161-6420 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2004-05-01 |
| Start Page: | 992 |
| End Page: | 996 |
| Language: | English |
| DOI: | 10.1016/j.ophtha.2003.08.036 |
| PROVIDER: | scopus |
| PUBMED: | 15121379 |
| DOI/URL: | |
| Notes: | Ophthalmology -- Cited By (since 1996):8 -- Export Date: 16 June 2014 -- CODEN: OPHTD -- Source: Scopus |
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