Cancer immunotherapy: Breaking the barriers to harvest the crop Journal Article
| Authors: | Pardoll, D.; Allison, J. |
| Article Title: | Cancer immunotherapy: Breaking the barriers to harvest the crop |
| Abstract: | Successful translation of modern molecular immunology into effective cancer immunotherapy is threatened by regulatory barriers and challenges to the development of novel agents and combinatorial strategies through effective public-private partnerships. For its promise to be fully realized, both the National Cancer Institute and Food and Drug Administration must take active steps to help academic investigators and companies jointly navigate the pathways from laboratory to clinic. |
| Keywords: | review; united states; united states food and drug administration; antineoplastic agent; neoplasms; cancer immunotherapy; cd40 ligand; food and drug administration; drug screening; cancer inhibition; drug research; immunotherapy; cancer vaccine; clinical research; immunomodulation; drug combinations; vaccine production; cytotoxic t lymphocyte antigen 4; flt3 ligand; toll like receptor; national institutes of health (u.s.); b7 antigen; government regulation; teamwork; drug industry; academic medical centers; interinstitutional relations; allergy and immunology; humans; human; priority journal |
| Journal Title: | Nature Medicine |
| Volume: | 10 |
| Issue: | 9 |
| ISSN: | 1078-8956 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2004-09-01 |
| Start Page: | 887 |
| End Page: | 892 |
| Language: | English |
| DOI: | 10.1038/nm0904-887 |
| PROVIDER: | scopus |
| PUBMED: | 15340404 |
| DOI/URL: | |
| Notes: | Nat. Med. -- Cited By (since 1996):83 -- Export Date: 16 June 2014 -- CODEN: NAMEF -- Source: Scopus |
