Meta-analyses of the effect of false-positive mammograms on generic and specific psychosocial outcomes Journal Article


Authors: Salz, T.; Richman, A. R.; Brewer, N. T.
Article Title: Meta-analyses of the effect of false-positive mammograms on generic and specific psychosocial outcomes
Abstract: Objectives: While a previous meta-analysis found that false-positive mammography results affect women's likelihood of returning for screening, effects on well being have yet to be meta-analyzed. We investigated whether the effects of false-positive mammograms on women's well-being are limited to outcomes specific to breast cancer. Methods: We searched MEDLINE for studies of the psychosocial effects of false-positive results of routine screening mammography. We pooled effect sizes using random effects meta-analysis. Results: Across 17 studies (n=20 781), receiving a false-positive mammogram the result was associated with differences in all eight breast-cancer-specific outcomes that we examined. These included greater anxiety and distress about breast cancer as well as more frequent breast self-exams and higher perceived effectiveness of screening mammography. False positives were associated with only one of six generic outcomes (i.e. generalized anxiety), and this effect size was small. Conclusions: False-positive mammograms influenced women's well-being, but the effects were limited to breast-cancer-specific outcomes. Researchers should include disease-specific measures in future studies of the consequences of false-positive mammograms. © 2010 John Wiley & Sons, Ltd.
Keywords: adult; major clinical study; review; outcome assessment; breast cancer; health behavior; mass screening; breast neoplasms; oncology; time factors; depression; mammography; distress syndrome; medline; attitude; clinical effectiveness; anxiety; fear; false positive result; false positive reactions; psychological well being; stress, psychological; wellbeing; breast neoplasm; false positive; breast self examination; social belief; somatization
Journal Title: Psycho-Oncology
Volume: 19
Issue: 10
ISSN: 1057-9249
Publisher: John Wiley & Sons  
Date Published: 2010-10-01
Start Page: 1026
End Page: 1034
Language: English
DOI: 10.1002/pon.1676
PUBMED: 20882572
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 20 April 2011" - "CODEN: POJCE" - "Source: Scopus"
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  1. Talya Salz
    67 Salz