In vivo reflectance-mode confocal scanning laser microscopy in dermatology Journal Article


Authors: Gonzalez, S.; Gilaberte-Calzada, Y.; González-Rodríguez, A.; Torres, A.; Mihm, M. C. Jr; James, W. D.
Article Title: In vivo reflectance-mode confocal scanning laser microscopy in dermatology
Title Series: Advances in Dermatology
Abstract: RCM offers tremendous potential for the advancement of medical research and clinical care. In research, it offers benefits both ex vivo and in vivo. Ex vivo, it can allow us to sample tissue and evaluate it noninvasively to determine what further testing - on the same exact tissue - may be helpful. In vivo RCM can be used to study normal or pathophysiologic processes in real-time noninvasively and by the same technique sequentially over time. Immunologic events previously only studied ex vivo or by static images can be traced from their inception to completion (Table 1). (Table Presented) The potential of RCM in vivo is tremendous. How would our world change if we could noninvasively diagnose skin lesions and, with the advent of new minimally invasive therapies, administer treatment and noninvasively monitor that treatment? The potential to allow better medical care based on actual visualization of therapeutic response and healing is obvious. Much like early X-ray and ultrasound imaging, RCM is in its infancy. It is only a matter of time and continued persistent research that will lead to similar success and utility for RCM. Copyright 2004, Mosby, Inc. All rights reserved.
Keywords: treatment outcome; histopathology; review; squamous cell carcinoma; melanoma; actinic keratosis; basal cell carcinoma; confocal microscopy; skin defect; microscopy, confocal; pathology; psoriasis; disease severity; evaluation; instrumentation; melanocytic nevus; skin disease; dermatology; skin diseases; confocal laser microscopy; skin infection; cytodiagnosis; contact dermatitis; humans; human
Journal Title: Advances in Dermatology
Volume: 20
ISSN: 0882-0880
Publisher: Elsevier Inc.  
Date Published: 2004-01-01
Start Page: 371
End Page: 387
Language: English
PROVIDER: scopus
PUBMED: 15544208
DOI/URL:
Notes: Book chapter 14 -- Adv. Dermatol. -- Cited By (since 1996):14 -- Export Date: 16 June 2014 -- Source: Scopus
Citation Impact
MSK Authors
  1. Salvador Gonzalez Rodriguez
    203 Rodriguez