Resurrecting treatment histories of dead patients: A study design that should be laid to rest Journal Article


Authors: Bach, P. B.; Schrag, D.; Begg, C. B.
Article Title: Resurrecting treatment histories of dead patients: A study design that should be laid to rest
Abstract: In this article we address whether studies of care rendered to patients prior to their death ("studies of decedents") produce an accurate portrait of care provided to patients who are dying. Studies of decedents typically analyze the care provided to patients over a defined interval antecedent to death. Studies of dying patients analyze care provided to patients subsequent to the time that their terminal status is perceived. We address whether 2 fundamental differences between studies of decedents and studies of the dying-the ways that subjects are identified and the time periods that are examined-lead to differences in interpretation of study results. Using examples from population-based cohorts of individuals with cancer, we show that both the differences in subject selection and time period introduce very substantial biases into studies of decedents. We conclude that studying care received prior to death can lead to invalid conclusions about the quality or type of care provided to dying patients.
Keywords: cancer chemotherapy; cancer survival; treatment outcome; aged; major clinical study; review; united states; cancer patient; cancer diagnosis; neoplasms; metastasis; breast cancer; lung non small cell cancer; cohort analysis; cancer mortality; health care cost; medicare; patient care; death; colon cancer; outcome and process assessment (health care); terminal care; bias (epidemiology); dying; quality of health care; medical history taking; humans; human; priority journal
Journal Title: JAMA - Journal of the American Medical Association
Volume: 292
Issue: 22
ISSN: 0098-7484
Publisher: American Medical Association  
Date Published: 2004-12-08
Start Page: 2765
End Page: 2770
Language: English
DOI: 10.1001/jama.292.22.2765
PROVIDER: scopus
PUBMED: 15585737
DOI/URL:
Notes: J. Am. Med. Assoc. -- Cited By (since 1996):77 -- Export Date: 16 June 2014 -- CODEN: JAMAA -- Source: Scopus
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  1. Colin B Begg
    307 Begg
  2. Deborah Schrag
    238 Schrag
  3. Peter Bach
    255 Bach