A randomized controlled trial of a cardiopulmonary resuscitation video in advance care planning for progressive pancreas and hepatobiliary cancer patients Journal Article


Authors: Epstein, A. S.; Volandes, A. E.; Chen, L. Y.; Gary, K. A.; Li, Y.; Agre, P.; Levin, T. T.; Reidy, D. L.; Meng, R. D.; Segal, N. H.; Yu, K. H.; Abou-Alfa, G. K.; Janjigian, Y. Y.; Kelsen, D. P.; O'Reilly, E. M.
Article Title: A randomized controlled trial of a cardiopulmonary resuscitation video in advance care planning for progressive pancreas and hepatobiliary cancer patients
Abstract: Background: Cardiopulmonary resuscitation (CPR) is an important advance directive (AD) topic in patients with progressive cancer; however such discussions are challenging. Objective: This study investigates whether video educational information about CPR engenders broader advance care planning (ACP) discourse. Methods: Patients with progressive pancreas or hepatobiliary cancer were randomized to an educational CPR video or a similar CPR narrative. The primary end-point was the difference in ACP documentation one month posttest between arms. Secondary end-points included study impressions; pre- and post-intervention knowledge of and preferences for CPR and mechanical ventilation; and longitudinal patient outcomes. Results: Fifty-six subjects were consented and analyzed. Rates of ACP documentation (either formal ADs or documented discussions) were 40% in the video arm (12/30) compared to 15% in the narrative arm (4/26), OR=3.6 [95% CI: 0.9-18.0], p=0.07. Post-intervention knowledge was higher in both arms. Posttest, preferences for CPR had changed in the video arm but not in the narrative arm. Preferences regarding mechanical ventilation did not change in either arm. The majority of subjects in both arms reported the information as helpful and comfortable to discuss, and they recommended it to others. More deaths occurred in the video arm compared to the narrative arm, and more subjects died in hospice settings in the video arm. Conclusions: This pilot randomized trial addressing downstream ACP effects of video versus narrative decision tools demonstrated a trend towards more ACP documentation in video subjects. This trend, as well as other video effects, is the subject of ongoing study. © Copyright 2013, Mary Ann Liebert, Inc.
Keywords: adult; treatment outcome; aged; aged, 80 and over; middle aged; major clinical study; cancer growth; liver neoplasms; cancer patient; pancreas cancer; pancreatic neoplasms; odds ratio; patient education as topic; videorecording; confidence intervals; patient care; medical information; death; medical education; pilot study; pilot projects; disease progression; medical documentation; hospice; biliary tract neoplasms; resuscitation; artificial ventilation; patient preference; randomized controlled trial (topic); video recording; narrative; cardiopulmonary resuscitation; hepatobiliary system cancer; advance care planning; discourse analysis
Journal Title: Journal of Palliative Medicine
Volume: 16
Issue: 6
ISSN: 1096-6218
Publisher: Mary Ann Liebert, Inc  
Date Published: 2013-06-01
Start Page: 623
End Page: 631
Language: English
DOI: 10.1089/jpm.2012.0524
PROVIDER: scopus
PUBMED: 23725233
PMCID: PMC5586157
DOI/URL:
Notes: --- - "Export Date: 1 July 2013" - "CODEN: JPAMF" - "Source: Scopus"
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MSK Authors
  1. Yuelin Li
    222 Li
  2. Neil Howard Segal
    210 Segal
  3. Ghassan Abou-Alfa
    571 Abou-Alfa
  4. Tomer T Levin
    62 Levin
  5. Diane Lauren Reidy
    294 Reidy
  6. Yelena Yuriy Janjigian
    400 Janjigian
  7. Kenneth Ho-Ming Yu
    164 Yu
  8. Andrew Saul Epstein
    159 Epstein
  9. Raymond De Meng
    7 Meng
  10. Eileen O'Reilly
    790 O'Reilly
  11. David P Kelsen
    538 Kelsen
  12. Patricia A Agre
    21 Agre
  13. Ling Yun Chen
    23 Chen
  14. Kristen A Gary
    8 Gary