Mucoepidermoid carcinoma of the bronchus presenting with a negative chest X-ray and normal pulmonary function in two teenagers: Two case reports and review of the literature Journal Article


Authors: Giusti, R. J.; Flores, R. M.
Article Title: Mucoepidermoid carcinoma of the bronchus presenting with a negative chest X-ray and normal pulmonary function in two teenagers: Two case reports and review of the literature
Abstract: Two adolescents presented with a history of dyspnea upon exertion and cough. In both cases, the chest X-ray and pulmonary function testing, including flow-volume loop, were normal. A bronchial tumor was diagnosed by CT scan, which was ordered after each patient had an episode of hemoptysis. The sedimentation rate was the only abnormal laboratory test in both cases. Mucoepidermoid carcinoma of the bronchus, a rare tumor in childhood, was found at pathology in both cases. There was no evidence of metastases to local lymph nodes or distal sites. There were 47 previously reported cases in children. Recurrent pneumonia and persistent cough were the most common presenting findings. These tumors are of low-grade malignant potential but they can become locally invasive, extending into cartilage and surrounding soft tissue. Prognosis is good with complete resection. © 2004 Wiley-Liss, Inc.
Keywords: adolescent; human tissue; treatment outcome; cancer surgery; human cell; clinical feature; histopathology; anamnesis; case report; lymph node metastasis; cancer grading; treatment indication; computer assisted tomography; image analysis; diagnosis, differential; childhood cancer; coughing; dyspnea; pneumonia; postoperative complication; cancer invasion; soft tissue; laboratory test; indometacin; literature; recurrent disease; lung carcinoma; bronchoscopy; bronchus; thorax radiography; adenosquamous carcinoma; carcinoma, mucoepidermoid; pericardial effusion; lung function test; lobectomy; bronchus tumor; bronchial neoplasms; hemoptysis; respiratory function tests; cartilage; bronchial adenoma; humans; prognosis; human; male; female; priority journal; article; tracheal reconstruction; lung flow volume curve; sedimentation rate
Journal Title: Pediatric Pulmonology
Volume: 37
Issue: 1
ISSN: 8755-6863
Publisher: Wiley Liss, Inc  
Date Published: 2004-01-01
Start Page: 81
End Page: 84
Language: English
DOI: 10.1002/ppul.10390
PROVIDER: scopus
PUBMED: 14679495
DOI/URL:
Notes: Pediatr. Pulmonol. -- Cited By (since 1996):15 -- Export Date: 16 June 2014 -- CODEN: PEPUE -- Source: Scopus
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  1. Raja Flores
    108 Flores