Primary follicular lymphoma of the testis: Excellent outcome following surgical resection without adjuvant chemotherapy Journal Article


Authors: Heller, K. N.; Teruya-Feldstein, J.; La Quaglia, M. P.; Wexler, L. H.
Article Title: Primary follicular lymphoma of the testis: Excellent outcome following surgical resection without adjuvant chemotherapy
Abstract: The authors report a case of follicular lymphoma of the testis in a 3-year-old boy. Follicular lymphoma of childhood is rare, accounting for less than 5% of all non-Hodgkin lymphomas in the pediatric population. Children with follicular NHL have typically been described as presenting with localized disease, with a preponderance of male patients. The authors conducted a comprehensive review of the literature and found that this patient is the only child reported to have localized follicular lymphoma of the testis successfully treated without systemic chemotherapy. In all previously reported cases, a favorable outcome was seen following surgical resection and chemotherapy. This patient has remained disease-free for more than 2 years after surgical resection alone. The successful outcome in this case following surgical resection, without postoperative adjuvant chemotherapy, suggests that localized follicular non-Hodgkin lymphoma in children may not be associated with occult systemic disease and that subsequent chemotherapy may not be necessary for cure.
Keywords: child; preschool child; treatment outcome; child, preschool; cancer surgery; case report; cancer adjuvant therapy; postoperative care; chemotherapy, adjuvant; chemotherapy; treatment; electron microscopy; tumor markers, biological; steroid; fluorescence in situ hybridization; bone marrow biopsy; cancer cytodiagnosis; testicular neoplasms; surgery; immunophenotyping; orchiectomy; testis cancer; follicular lymphoma; lymphoma, follicular; beta adrenergic receptor stimulating agent; gallium; testes; atopic dermatitis; testis biopsy; humans; human; male; priority journal; article
Journal Title: Journal of Pediatric Hematology/Oncology
Volume: 26
Issue: 2
ISSN: 1077-4114
Publisher: Lippincott Williams & Wilkins  
Date Published: 2004-02-01
Start Page: 104
End Page: 107
Language: English
DOI: 10.1097/00043426-200402000-00007
PROVIDER: scopus
PUBMED: 14767197
DOI/URL:
Notes: J. Pediatr. Hematol. Oncol. -- Cited By (since 1996):22 -- Export Date: 16 June 2014 -- CODEN: JPHOF -- Source: Scopus
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  1. Julie T Feldstein
    297 Feldstein
  2. Leonard H Wexler
    191 Wexler
  3. Kevin Heller
    2 Heller