Nonconvulsive status epilepticus in patients with cancer: Imaging abnormalities Journal Article

  


Authors: Hormigo, A.; Liberato, B.; Lis, E.; Deangelis, L. M.
Article Title: Nonconvulsive status epilepticus in patients with cancer: Imaging abnormalities
Abstract: Backgrounds: Convulsive status epilepticus may cause reversible neuroimaging abnormalities. These cortical changes have been reported rarely in association with nonconvulsive status epilepticus. Objectives: To describe patients with cancer who had reversible magnetic resonance (MR) imaging abnormalities from nonconvulsive status epilepticus and whose altered mental status and MR imaging findings were initially considered to result from a structural lesion related to their underlying tumor. Design: Retrospective study. Settings: Department of Neurology at Memorial Sloan-Kettering Cancer Center, New York, NY. Patients: Eight patients with a diagnosis of nonconvulsive status epilepticus who underwent MR imaging. Results: Enhancing cortical abnormalities were observed on MR images in 4 (50%) of 8 patients with cancer who had impaired mental status and an electroencephalogram demonstrating seizure activity. Follow-up MR images showed neuroimaging improvement or resolution in all patients. Conclusions: Cortical enhancement on MR images in patients with cancer who have altered mental status may be due to nonconvulsive status epilepticus and not recurrent or metastatic tumor. If electroencephalography is not immediately available at initial evaluation, a trial of anticonvulsant therapy deserves consideration.
Keywords: adult; clinical article; aged; aged, 80 and over; middle aged; retrospective studies; gadolinium; neuroimaging; nuclear magnetic resonance imaging; positron emission tomography; follow up; brain neoplasms; magnetic resonance imaging; brain cortex; retrospective study; brain metastasis; seizure; anticonvulsive agent; cerebral cortex; mental health; electroencephalogram; electroencephalography; tomography, emission-computed; epileptic state; convulsion; status epilepticus; cancer; humans; human; male; female; priority journal; article; nonconvulsive epileptic state
Journal Title: Archives of Neurology
Volume: 61
Issue: 3
ISSN: 0003-9942
Publisher: American Medical Association  
Date Published: 2004-03-01
Start Page: 362
End Page: 365
Language: English
DOI: 10.1001/archneur.61.3.362
PROVIDER: scopus
PUBMED: 15023812
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-1542268250&partnerID=40&md5=4b262335fcc47967e15e49339584050e
Notes: Arch. Neurol. -- Cited By (since 1996):23 -- Export Date: 16 June 2014 -- CODEN: ARNEA -- Source: Scopus
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MSK Authors
  1. Lisa De Angelis
    576 De Angelis
  2. Eric Lis
    138 Lis
  3. Adilia Hormigo
    49 Hormigo
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