Laparoscopic restaging of early stage invasive adnexal tumors: A 10-year experience Journal Article


Authors: Leblanc, E.; Querleu, D.; Narducci, F.; Occelli, B.; Papageorgiou, T.; Sonoda, Y.
Article Title: Laparoscopic restaging of early stage invasive adnexal tumors: A 10-year experience
Abstract: Surgical staging of apparent early stage adnexal carcinoma provides indispensable information. A significant number of patients are referred to tertiary centers with inadequate staging information. We report on our experience with late results of laparoscopic restaging procedure in uncompletely managed early adnexal carcinomas. Materials and methods. From 1991 to 2001, 53 laparoscopic restaging operations were performed: 42 patients were restaged early after initial surgery for an ovarian carcinoma (OC) in 35 of them, and for fallopian tube carcinomas (FTCs) in 7 others. Eleven patients were assessed as a second-look procedure, after six courses of platinum-based chemotherapy indicated for a high-risk tumor. The procedure systematically followed the guidelines of laparotomy. Results. All except one (adhesions) procedures were successfully completed. Operative room time averaged 238 min and hospital stay 3.1 days. Only one major complication required laparotomy (1.8%). In the primary restaging group, eight patients were upstaged (19%) and were given chemotherapy. After a 54-month median follow-up, 3 out of the 34 remaining patients diagnosed as stage IA grades 1-2 (6.4%) recurred and died. In the group of 11 second-look operations, 4 were found positive after chemotherapy. One of the positive patient recurred and died. Conclusions. Laparoscopy seems to be an acceptable technical option to perform restaging of apparently early adnexal carcinomas. It spares the patients the discomfort of repeat laparotomy. Long-term outcome results suggest that laparoscopic staging, provided it meets the standards, accurately detects the patients who need chemotherapy and safely select the patients who can be proposed surgery only. © 2004 Elsevier Inc. All rights reserved.
Keywords: adolescent; adult; cancer chemotherapy; clinical article; controlled study; middle aged; surgical technique; cancer recurrence; cancer risk; cancer staging; follow up; follow-up studies; antineoplastic agent; cancer diagnosis; neoplasm staging; laparoscopy; laparotomy; prospective studies; ovarian neoplasms; practice guideline; postoperative complication; cancer invasion; hospitalization; operation duration; carcinoma; ovary carcinoma; uterine tube carcinoma; fallopian tube neoplasms; second look surgery; operating room; adnexa disease; humans; human; female; priority journal; article; adnexal tumor; genital tract tumor
Journal Title: Gynecologic Oncology
Volume: 94
Issue: 3
ISSN: 0090-8258
Publisher: Elsevier Inc.  
Date Published: 2004-09-01
Start Page: 624
End Page: 629
Language: English
DOI: 10.1016/j.ygyno.2004.05.052
PROVIDER: scopus
PUBMED: 15350350
DOI/URL:
Notes: Gynecol. Oncol. -- Cited By (since 1996):72 -- Export Date: 16 June 2014 -- CODEN: GYNOA -- Source: Scopus
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  1. Yukio Sonoda
    472 Sonoda