Use of established nomograms to predict non-sentinel lymph node metastasis Journal Article


Authors: Matsen, C.; Van Zee, K. J.
Article Title: Use of established nomograms to predict non-sentinel lymph node metastasis
Abstract: Sentinel node biopsy has replaced routine axillary node dissection for women with clinically node-negative breast cancer. The development of nomograms, predictive models that enable individualized risk estimation, has enabled identification of women that are at low or high risk of residual non-sentinel node disease after a positive sentinel node biopsy, and have been widely validated. Furthermore, such models have been shown to predict risk of regional recurrence, risk of non-sentinel node involvement after neoadjuvant chemotherapy, and risk of four or more positive axillary nodes. Together with the panoply of other data, these mathematical models contribute to optimum and individualized decision making for a woman with breast cancer. © Springer Science+Business Media 2014.
Keywords: cancer surgery; review; validation process; lymph node metastasis; sentinel node; cancer diagnosis; breast cancer; mastectomy; calibration; prediction; mathematical model; adjuvant chemotherapy; neoadjuvant chemotherapy; decision making; validation; nomogram; completion axillary lymph node dissection; predictive models; nodal metastasis; axillary nodes; post-mastectomy radiation; predictive tools; human; non-sentinel node metastasis; regional recurrence; non sentinel lymph node metastasis
Journal Title: Current Breast Cancer Reports
Volume: 6
Issue: 1
ISSN: 1943-4588
Publisher: Springer  
Date Published: 2014-01-01
Start Page: 24
End Page: 31
Language: English
DOI: 10.1007/s12609-013-0137-5
PROVIDER: scopus
DOI/URL:
Notes: Curr. Breast Cancer Rep. -- Export Date: 2 June 2014 -- Source: Scopus
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  1. Kimberly J Van Zee
    293 Van Zee
  2. Cindy Brown Matsen
    7 Matsen