Authors: | Moo, T. A.; Sanford, R.; Dang, C.; Morrow, M. |
Article Title: | Overview of breast cancer therapy |
Abstract: | Breast cancer treatment is multidisciplinary. Most women with early stage breast cancer are candidates for breast-conserving surgery with radiotherapy or mastectomy. The risk of local recurrence and the chance of survival does not differ with these approaches. Sentinel node biopsy is used for axillary staging, and individualized approaches are minimizing the need for axillary dissection in women with positive sentinel nodes. Adjuvant systemic therapy is used in most women based on proven survival benefit, and molecular profiling to individualize treatment based on risk is now a clinical reality for patients with hormone receptor–positive cancers. © 2018 Elsevier Inc. |
Keywords: | cancer survival; excision; major clinical study; review; cancer recurrence; adjuvant therapy; cancer staging; nuclear magnetic resonance imaging; cancer grading; breast cancer; mastectomy; tumor volume; myalgia; epidermal growth factor receptor 2; local therapy; vaginal dryness; cancer therapy; high risk patient; hodgkin disease; exemestane; arthralgia; axillary lymph node; preoperative period; mammography; systematic review; vein thrombosis; partial mastectomy; reoperation; tamoxifen; dermatomyositis; systemic lupus erythematosus; hot flush; letrozole; osteoporosis; physical examination; neoadjuvant chemotherapy; lifestyle modification; anastrozole; endocrine therapy; lumpectomy; osteopenia; breast-conserving therapy; triple negative breast cancer; ovary function; tumor invasion; premature ovarian failure; polymyositis; breast cancer surveillance; estrogen receptor positive breast cancer; human; priority journal; breast cancer therapy |
Journal Title: | PET Clinics |
Volume: | 13 |
Issue: | 3 |
ISSN: | 1556-8598 |
Publisher: | Elsevier Inc. |
Date Published: | 2018-07-01 |
Start Page: | 339 |
End Page: | 354 |
Language: | English |
DOI: | 10.1016/j.cpet.2018.02.006 |
PROVIDER: | scopus |
PMCID: | PMC6092031 |
PUBMED: | 30100074 |
DOI/URL: | |
Notes: | Review -- Export Date: 1 August 2018 -- Source: Scopus |