Sister acts: Coordinating DNA replication and cohesion establishment Journal Article

   


Authors: Sherwood, R.; Takahashi, T. S.; Jallepalli, P. V.
Article Title: Sister acts: Coordinating DNA replication and cohesion establishment
Abstract: The ring-shaped cohesin complex links sister chromatids and plays crucial roles in homologous recombination and mitotic chromosome segregation. In cycling cells, cohesin's ability to generate cohesive linkages is restricted to S phase and depends on loading and establishment factors that are intimately connected to DNA replication. Here we review how cohesin is regulated by the replication machinery, as well as recent evidence that cohesin itself influences how chromosomes are replicated. © 2010 by Cold Spring Harbor Laboratory Press.
Keywords: unclassified drug; review; nonhuman; dna replication; protein function; mitosis; cohesin; chromosome; cell cycle proteins; chromosomal proteins, non-histone; cell cycle; cell cycle s phase; sister chromatid; protein dna binding; protein protein interaction; dna structure; cell adhesion; chromosome pairing; acyltransferase; chromosomes; chromosome replication; acetylation; roberts syndrome; chromatids; sister chromatid cohesion; eco1 protein
Journal Title: Genes and Development
Volume: 24
Issue: 24
ISSN: 0890-9369
Publisher: Cold Spring Harbor Laboratory Press  
Date Published: 2010-12-15
Start Page: 2723
End Page: 2731
Language: English
DOI: 10.1101/gad.1976710
PUBMED: 21159813
PROVIDER: scopus
PMCID: PMC3003188
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-78650226331&partnerID=40&md5=3024c8865a46e1152ef02ecbf515a6de
Notes: --- - "Export Date: 20 April 2011" - "CODEN: GEDEE" - "Source: Scopus"
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MSK Authors
  1. Prasad V Jallepalli
    34 Jallepalli
  2. Rebecca Sherwood
    2 Sherwood
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