Sclerosed hemangioma of the liver: Concordance of MRI features with histologic characteristics Journal Article


Authors: Ridge, C. A.; Shia, J.; Gerst, S. R.; Do, R. K. G.
Article Title: Sclerosed hemangioma of the liver: Concordance of MRI features with histologic characteristics
Abstract: Purpose To correlate the MRI features of sclerosed hemangiomas with histologic appearance. Materials and Methods A medical record search identified patients with sclerosed hemangioma who underwent MRI and biopsy/resection from January 2000 to March 2012 for this retrospective institutional review board approved study. Two radiologists independently performed image analysis. A pathologist evaluated lesion histologic characteristics. Results Twelve patients (median age 65; range 41-78 years) were included; 7/12 patients had typical hemangiomas which were also analyzed. Sclerosed hemangiomas were less often moderately T2 hyperintense (5/11 45%; compared with 7/7, 100%; P = 0.0377) and demonstrated moderate arterial phase enhancement less frequently (4/12, 33% compared with 7/7, 100%; P = 0.0128) than typical hemangiomas. Markedly sclerosed hemangiomas (N = 7) exhibited the least "typical" findings, including mild T2 hyperintensity (5/7; 71%), absent arterial phase enhancement (4/7; 57%), mild portal venous phase enhancement (6/7; 86%), and absent centripetal fill-in (6/7; 86%). Arterial phase hyperenhancement occurred more often in mild/moderately sclerosed hemangiomas (3/5; 60%) compared with markedly sclerosed hemangiomas (1/7; 14%). Conclusion Sclerosed hemangiomas exhibit MRI features that appear to correspond with the degree of sclerosis. These features coupled with the presence of other typical hemangiomas may aid in prospectively diagnosing sclerosed hemangioma. © 2013 Wiley Periodicals, Inc.
Keywords: adult; clinical article; human tissue; aged; middle aged; clinical feature; review; comparative study; nuclear magnetic resonance imaging; magnetic resonance imaging; image analysis; medical record review; liver; radiologist; diagnosis; liver hemangioma; liver biopsy; hemangioma; sclerosis; liver histology; human; male; female; priority journal; sclerosed liver hemangioma
Journal Title: Journal of Magnetic Resonance Imaging
Volume: 39
Issue: 4
ISSN: 1053-1807
Publisher: Wiley Blackwell  
Date Published: 2014-04-01
Start Page: 812
End Page: 818
Language: English
DOI: 10.1002/jmri.24228
PROVIDER: scopus
PUBMED: 24783239
DOI/URL:
Notes: Export Date: 1 May 2014 -- CODEN: JMRIF -- Source: Scopus
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  1. Jinru Shia
    724 Shia