Radiation-induced SVC syndrome Journal Article


Authors: Mehta, S. V.; Koo, D. J.
Article Title: Radiation-induced SVC syndrome
Abstract: A 69-year-old woman with a history of Hodgkin's lymphoma at age 17 was admitted to our hospital with 3 weeks of progressive dyspnoea on exertion. Her medical history and physical exam were concerning for superior vena cava (SVC) syndrome and while her workup did indeed reveal such, its aetiology was not due to a compressive mass associated with malignancy. Rather, she developed chronic thromboses in the setting of radiation-induced venous fibrosis. This case report details her case and explains the key clinical concerns, pathophysiology and incidence of radiation-induced SVC syndrome. Copyright 2014 BMJ Publishing Group. All rights reserved.
Keywords: aged; antibiotic agent; disease course; case report; hypertension; pathophysiology; follow up; lymph node dissection; breast cancer; differential diagnosis; incidence; furosemide; hodgkin disease; dyspnea; pneumonia; lung embolism; vein thrombosis; surgical risk; warfarin; tamoxifen; recurrent disease; pleura effusion; hospital admission; thorax radiography; echocardiography; heart left ventricle ejection fraction; lung function test; lung fibrosis; epistaxis; congestive heart failure; disease exacerbation; diuretic agent; heart right ventricle failure; superior cava vein syndrome; thrombectomy; medical history; pleura thickening; artery occlusion; leg swelling; chest tightness; iron deficiency anemia; thorax scintiscanning; carvedilol; paroxysmal dyspnea; mitral valve regurgitation; human; female; priority journal; article; losartan; constrictive pericarditis; heart atrium enlargement; radiation induced superior cava vein syndrome; subclavian artery stenosis; total lung capacity
Journal Title: BMJ Case Reports
ISSN: 1757-790X
Publisher: BMJ Publishing Group Ltd.  
Date Published: 2014-02-19
Language: English
DOI: 10.1136/bcr-2013-203446
PROVIDER: scopus
PUBMED: 24554686
PMCID: PMC3931950
DOI/URL:
Notes: Export Date: 1 May 2014 -- Source: Scopus
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  1. Douglas Koo
    16 Koo