Acute pain relief after mantram meditation in children with neuroblastoma undergoing anti-GD2 monoclonal antibody therapy Journal Article

  

Authors:	Ahmed, M.; Modak, S.; Sequeira, S.
Article Title:	Acute pain relief after mantram meditation in children with neuroblastoma undergoing anti-GD2 monoclonal antibody therapy
Abstract:	Nonpharmacologic, mind-body interventions are used to reduce anxiety in pediatric patients. Anti-ganglioside GD2 monoclonal antibody (anti-GD2 MoAb 3F8) therapy is the standard of care for high-risk neuroblastoma and pain is its major side effect. We performed a retrospective analysis of children undergoing anti-GD2 MoAb 3F8 treatment who received guided meditation. Meditation involved concentrating on the repetition of rhythmic, melodic sounds purported to slow breathing and induce a relaxation response. A total of 71% patients completed a session at first (n=19) or second attempt (n=5). Patients received fewer analgesic doses to manage anti-GD2 MoAb 3F8-induced pain when participating in meditation (n=17, mean=-0.4 dose, P<0.01). Mantram meditation is a feasible outpatient intervention associated with reduced analgesic requirements. Copyright © 2013 by Lippincott Williams & Wilkins.
Keywords:	adolescent; child; clinical article; controlled study; child, preschool; retrospective studies; unclassified drug; antineoplastic agents; cancer immunotherapy; pain; granulocyte macrophage colony stimulating factor; retrospective study; monoclonal antibody; antibodies, monoclonal; feasibility study; neuroblastoma; clinical effectiveness; meditation; children; hydromorphone; analgesia; pain assessment; monoclonal antibody 3f8; gangliosides; heart rate; humans; human; male; female; priority journal; article; mantram; mantram meditation
Journal Title:	Journal of Pediatric Hematology/Oncology
Volume:	36
Issue:	2
ISSN:	1077-4114
Publisher:	Lippincott Williams & Wilkins
Date Published:	2014-03-01
Start Page:	152
End Page:	155
Language:	English
DOI:	10.1097/mph.0000000000000024
PROVIDER:	scopus
PUBMED:	24065045
DOI/URL:	http://www.scopus.com/inward/record.url?eid=2-s2.0-84896732479&partnerID=40&md5=63ba29fa48b58fc146fd7c1824e04bba
Notes:	Cited By (since 1996):1 -- Export Date: 2 April 2014 -- CODEN: JPHOF -- Source: Scopus