Authors: | Ahmed, M.; Modak, S.; Sequeira, S. |
Article Title: | Acute pain relief after mantram meditation in children with neuroblastoma undergoing anti-GD2 monoclonal antibody therapy |
Abstract: | Nonpharmacologic, mind-body interventions are used to reduce anxiety in pediatric patients. Anti-ganglioside GD2 monoclonal antibody (anti-GD2 MoAb 3F8) therapy is the standard of care for high-risk neuroblastoma and pain is its major side effect. We performed a retrospective analysis of children undergoing anti-GD2 MoAb 3F8 treatment who received guided meditation. Meditation involved concentrating on the repetition of rhythmic, melodic sounds purported to slow breathing and induce a relaxation response. A total of 71% patients completed a session at first (n=19) or second attempt (n=5). Patients received fewer analgesic doses to manage anti-GD2 MoAb 3F8-induced pain when participating in meditation (n=17, mean=-0.4 dose, P<0.01). Mantram meditation is a feasible outpatient intervention associated with reduced analgesic requirements. Copyright © 2013 by Lippincott Williams & Wilkins. |
Keywords: | adolescent; child; clinical article; controlled study; child, preschool; retrospective studies; unclassified drug; antineoplastic agents; cancer immunotherapy; pain; granulocyte macrophage colony stimulating factor; retrospective study; monoclonal antibody; antibodies, monoclonal; feasibility study; neuroblastoma; clinical effectiveness; meditation; children; hydromorphone; analgesia; pain assessment; monoclonal antibody 3f8; gangliosides; heart rate; humans; human; male; female; priority journal; article; mantram; mantram meditation |
Journal Title: | Journal of Pediatric Hematology/Oncology |
Volume: | 36 |
Issue: | 2 |
ISSN: | 1077-4114 |
Publisher: | Lippincott Williams & Wilkins |
Date Published: | 2014-03-01 |
Start Page: | 152 |
End Page: | 155 |
Language: | English |
DOI: | 10.1097/mph.0000000000000024 |
PROVIDER: | scopus |
PUBMED: | 24065045 |
DOI/URL: | |
Notes: | Cited By (since 1996):1 -- Export Date: 2 April 2014 -- CODEN: JPHOF -- Source: Scopus |