32P Brachytherapy conformal source model RIC-100 for high-dose-rate treatment of superficial disease: Monte Carlo calculations, diode measurements, and clinical implementation Journal Article
| Authors: | Cohen, G. N.; Munro, J. J. 3rd; Kirov, A.; LoSasso, T.; Yamada, Y.; Williamson, M.; Dauer, L. T.; Zaider, M. |
| Article Title: | 32P Brachytherapy conformal source model RIC-100 for high-dose-rate treatment of superficial disease: Monte Carlo calculations, diode measurements, and clinical implementation |
| Abstract: | Purpose A novel 32P brachytherapy source has been in use at our institution intraoperatively for temporary radiation therapy of the spinal dura and other localized tumors. We describe the dosimetry and clinical implementation of the source. Methods and Materials Dosimetric evaluation for the source was done with a complete set of MCNP5 Monte Carlo calculations preceding clinical implementation. In addition, the depth dose curve and dose rate were measured by use of an electron field diode to verify the Monte Carlo calculations. Calibration procedures using the diode in a custom-designed phantom to provide an absolute dose calibration and to check dose uniformity across the source area for each source before treatment were established. Results Good agreement was established between the Monte Carlo calculations and diode measurements. Quality assurance measurements results are provided for about 100 sources used to date. Clinical source calibrations were usually within 10% of manufacturer specifications. Procedures for safe handling of the source are described. Discussion Clinical considerations for using the source are discussed. © 2014 Elsevier Inc. |
| Journal Title: | International Journal of Radiation Oncology, Biology, Physics |
| Volume: | 88 |
| Issue: | 3 |
| ISSN: | 0360-3016 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2014-03-01 |
| Start Page: | 746 |
| End Page: | 752 |
| Language: | English |
| DOI: | 10.1016/j.ijrobp.2013.11.006 |
| PROVIDER: | scopus |
| PUBMED: | 24411623 |
| DOI/URL: | |
| Notes: | Export Date: 3 March 2014 -- CODEN: IOBPD -- Source: Scopus |
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