Zebrafish models of cancer: Progress and future challenges Journal Article


Authors: Yen, J.; White, R. M.; Stemple, D. L.
Article Title: Zebrafish models of cancer: Progress and future challenges
Abstract: The need for scalable strategies to probe the biological consequences of candidate cancer genes has never been more pressing. The zebrafish, with its capacity for high-throughput transgenesis, in vivo imaging and chemical/genetic screening, has ideal features for undertaking this task. Unique biological insights from zebrafish have already led to the identification of novel oncogenic drivers and small molecules being used to treat the human cancer. This review summarizes the recent main findings and describes pertinent areas where the zebrafish can greatly contribute to our understanding of cancer biology and treatment. © 2013 The Authors.
Journal Title: Current Opinion in Genetics and Development
Volume: 24
Issue: 1
ISSN: 0959-437X
Publisher: Elsevier Inc.  
Date Published: 2014-02-01
Start Page: 38
End Page: 45
Language: English
DOI: 10.1016/j.gde.2013.11.003
PROVIDER: scopus
PMCID: PMC4003353
PUBMED: 24657535
DOI/URL:
Notes: Export Date: 3 February 2014 -- CODEN: COGDE -- Source: Scopus
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MSK Authors
  1. Richard Mark White
    29 White
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