Inter-modality variation in gross tumor volume delineation in 18FDG-PET guided IMRT treatment planning for lung cancer Conference Paper
| Authors: | Song, Y.; Chan, M.; Burman, C.; Cann, D. |
| Title: | Inter-modality variation in gross tumor volume delineation in 18FDG-PET guided IMRT treatment planning for lung cancer |
| Conference Title: | 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society |
| Abstract: | Rapid advances in 18FDG-PET/CT technology and novel co-registration algorithms have created a strong interest in 18FDG-PET/CT's application in intensity modulated radiation therapy (IMRT) and image-guided radiation therapy (IGRT). Accurate target volume delineation, particularly identification of pathologically positive lymph nodes, could translate into favorable treatment outcome. However, gross tumor volume (GTV) delineation on both CT and 18FDG-PET is very sensitive to observer variation. The objectives of the study were to investigate the inter-modality variation in gross tumor volume delineation defined by two imaging modalities for lung cancer: CT and 18FDG-PET/CT and its dosimetric implications in intensity modulated radiation therapy (IMRT). |
| Keywords: | intensity modulated radiation therapy; radiation dose; positron emission tomography; methodology; radiopharmaceuticals; lung non small cell cancer; carcinoma, non-small-cell lung; lung neoplasms; radiotherapy dosage; lung tumor; diagnostic agent; radiotherapy, intensity-modulated; fluorodeoxyglucose f 18; fluorodeoxyglucose f18; positron-emission tomography; radiopharmaceutical agent; radiography; radiotherapy planning, computer-assisted; image processing, computer-assisted; image processing; computer assisted radiotherapy; article |
| Journal Title | IEEE Engineering in Medicine and Biology Society. Conference Proceedings |
| Volume: | 1 |
| Conference Dates: | 2006 Aug 30-Sep 3 |
| Conference Location: | New York, NY |
| ISBN: | 1557-170X |
| Publisher: | IEEE |
| Date Published: | 2006-08-01 |
| Start Page: | 3803 |
| End Page: | 3806 |
| Language: | English |
| PUBMED: | 17946204 |
| PROVIDER: | scopus |
| DOI: | 10.1109/IEMBS.2006.260257 |
| DOI/URL: | |
| Notes: | Export Date: 3 February 2014 -- Source: Scopus |
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