Carbon nanotubes as vaccine scaffolds Journal Article


Authors: Scheinberg, D. A.; McDevitt, M. R.; Dao, T.; Mulvey, J. J.; Feinberg, E.; Alidori, S.
Article Title: Carbon nanotubes as vaccine scaffolds
Abstract: Carbon nanotubes display characteristics that are potentially useful in their development as scaffolds for vaccine compositions. These features include stability in vivo, lack of intrinsic immunogenicity, low toxicity, and the ability to be appended with multiple copies of antigens. In addition, the particulate nature of carbon nanotubes and their unusual properties of rapid entry into antigen-presenting cells, such as dendritic cells, make them especially useful as carriers of antigens. Early attempts demonstrating carbon nanotube-based vaccines can be used in both infectious disease settings and cancer are promising. © 2013 Elsevier B.V.
Keywords: vaccines; adjuvants; carbon nanotubes; antigen presenting cells
Journal Title: Advanced Drug Delivery Reviews
Volume: 65
Issue: 15
ISSN: 0169-409X
Publisher: Elsevier Science, Inc.  
Date Published: 2013-12-01
Start Page: 2016
End Page: 2022
Language: English
DOI: 10.1016/j.addr.2013.07.013
PROVIDER: scopus
PMCID: PMC3855883
PUBMED: 23899863
DOI/URL:
Notes: Cited By (since 1996):1 -- Export Date: 2 January 2014 -- CODEN: ADDRE -- Source: Scopus
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MSK Authors
  1. Michael R Mcdevitt
    118 Mcdevitt
  2. Tao Dao
    59 Dao
  3. Joseph Justin Mulvey
    7 Mulvey