Carbon nanotubes as vaccine scaffolds Journal Article
| Authors: | Scheinberg, D. A.; McDevitt, M. R.; Dao, T.; Mulvey, J. J.; Feinberg, E.; Alidori, S. |
| Article Title: | Carbon nanotubes as vaccine scaffolds |
| Abstract: | Carbon nanotubes display characteristics that are potentially useful in their development as scaffolds for vaccine compositions. These features include stability in vivo, lack of intrinsic immunogenicity, low toxicity, and the ability to be appended with multiple copies of antigens. In addition, the particulate nature of carbon nanotubes and their unusual properties of rapid entry into antigen-presenting cells, such as dendritic cells, make them especially useful as carriers of antigens. Early attempts demonstrating carbon nanotube-based vaccines can be used in both infectious disease settings and cancer are promising. © 2013 Elsevier B.V. |
| Keywords: | vaccines; adjuvants; carbon nanotubes; antigen presenting cells |
| Journal Title: | Advanced Drug Delivery Reviews |
| Volume: | 65 |
| Issue: | 15 |
| ISSN: | 0169-409X |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2013-12-01 |
| Start Page: | 2016 |
| End Page: | 2022 |
| Language: | English |
| DOI: | 10.1016/j.addr.2013.07.013 |
| PROVIDER: | scopus |
| PMCID: | PMC3855883 |
| PUBMED: | 23899863 |
| DOI/URL: | |
| Notes: | Cited By (since 1996):1 -- Export Date: 2 January 2014 -- CODEN: ADDRE -- Source: Scopus |
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