Multimodality cardiovascular molecular imaging technology Journal Article


Authors: O'Donnell, M.; McVeigh, E. R.; Strauss, H. W.; Tanaka, A.; Bouma, B. E.; Tearney, G. J.; Guttman, M. A.; Garcia, E. V.
Article Title: Multimodality cardiovascular molecular imaging technology
Abstract: Cardiovascular molecular imaging is a new discipline that integrates scientific advances in both functional imaging and molecular probes to improve our understanding of the molecular basis of the cardiovascular system. These advances are driven by in vivo imaging of molecular processes in animals, usually small animals, and are rapidly moving toward clinical applications. Molecular imaging has the potential to revolutionize the diagnosis and treatment of cardiovascular disease. The 2 key components of all molecular imaging systems are the molecular contrast agents and the imaging system providing spatial and temporal localization of these agents within the body. They must deliver images with the appropriate sensitivity and specificity to drive clinical applications. As work in molecular contrast agents matures and highly sensitive and specific probes are developed, these systems will provide the imaging technologies required for translation into clinical tools. This is the promise of molecular medicine. Copyright © 2010 by the Society of Nuclear Medicine, Inc.
Keywords: review; nonhuman; nuclear magnetic resonance imaging; methodology; magnetic resonance imaging; sensitivity and specificity; animal; animals; biological model; models, biological; computer interface; user-computer interface; pathology; molecular imaging; diagnostic imaging; ultrasound; optical tomography; tomography, optical; three dimensional imaging; cardiovascular disease; cardiovascular diseases; cardiovascular system; echography; contrast medium; contrast media; image processing, computer-assisted; image processing; computer graphics; acoustics; molecular probe; ultrasonography; heart surgery; cardiovascular; multidisciplinary approach; cardiac imaging; percutaneous coronary intervention; radiation detector
Journal Title: Journal of Nuclear Medicine
Volume: 51
Issue: Suppl. 1
ISSN: 0161-5505
Publisher: Society of Nuclear Medicine  
Date Published: 2010-05-01
Start Page: 38S
End Page: 50S
Language: English
DOI: 10.2967/jnumed.109.068155
PUBMED: 20457794
PROVIDER: scopus
PMCID: PMC3010877
DOI/URL:
Notes: --- - "Export Date: 20 April 2011" - "CODEN: JNMEA" - "Source: Scopus"
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  1. Harry W Strauss
    164 Strauss
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