Randomized clinical trials in gastric cancer Journal Article


Authors: Mezhir, J. J.; Pillarisetty, V.; Shah, M.; Coit, D. G.
Article Title: Randomized clinical trials in gastric cancer
Abstract: Minimally invasive resection has emerged as a surgical technique for gastric cancer, and there has been continued investigation to determine the appropriate extent of lymphadenectomy in gastric cancer patients. There has also been significant progress in evaluating the role of chemotherapeutic regimens used in the neoadjuvant and adjuvant settings for patients with resectable disease. We also summarize a selection of RCT trials focused on the perioperative care of the gastric cancer patient. © 2010 Elsevier Inc. All rights reserved.
Keywords: cancer survival; treatment outcome; clinical trial; drug tolerability; neutropenia; review; splenectomy; cisplatin; fluorouracil; cancer combination chemotherapy; drug dose reduction; drug efficacy; monotherapy; unspecified side effect; capecitabine; adjuvant therapy; cancer adjuvant therapy; cancer patient; cancer radiotherapy; neoadjuvant therapy; chemotherapy; lymph node metastasis; antineoplastic agent; lymph node dissection; laparoscopic surgery; anorexia; lymphadenectomy; controlled clinical trial; multiple cycle treatment; anemia; etoposide; leukopenia; lung disease; nausea; randomized controlled trial; abdominal abscess; randomized controlled trials as topic; continuous infusion; surgical approach; docetaxel; abdominal pain; fever; folinic acid; drug response; surgical infection; single drug dose; surgery; gastrectomy; surgical mortality; intermethod comparison; stomach cancer; epirubicin; mitomycin c; minimally invasive surgery; perioperative period; clarithromycin; oxaliplatin; antibiotic prophylaxis; stomach neoplasms; abdominal drainage; gastric cancer; roux y anastomosis; anastomosis leakage; cefazolin; lansoprazole; abdominal bleeding; eradication therapy; helicobacter infection; randomized clinical trial; 5 chloro 2,4 dihydroxypyridine plus oxonate potassium plus tegafur; amoxicillin; sultamicillin; bile reflux; endoscopic mucosal resection; gastrectomy billroth i; nose feeding; subphrenic abscess; total stomach resection
Journal Title: Surgical Oncology Clinics of North America
Volume: 19
Issue: 1
ISSN: 1055-3207
Publisher: Elsevier Inc.  
Date Published: 2010-01-01
Start Page: 81
End Page: 100
Language: English
DOI: 10.1016/j.soc.2009.09.011
PUBMED: 19914561
PROVIDER: scopus
DOI/URL:
Notes: --- - "Export Date: 20 April 2011" - "CODEN: SOCAF" - "Source: Scopus"
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  1. James John Mezhir
    13 Mezhir
  2. Manish Shah
    177 Shah
  3. Daniel Coit
    542 Coit