Molecular imaging: An innovative force in musculoskeletal radiology Journal Article
| Authors: | Wilmot, A.; Gieschler, S.; Behera, D.; Gade, T. P.; Reumann, M. K.; Biswal, S.; Mayer-Kuckuk, P. |
| Article Title: | Molecular imaging: An innovative force in musculoskeletal radiology |
| Abstract: | Objective. A review of the innovative role molecular imaging plays in musculoskeletal radiology is provided. Musculoskeletal molecular imaging is under development in four key areas: imaging the activity of osteoblasts and osteoclasts, imaging of molecular and cellular biomarkers of arthritic joint destruction, cellular imaging of osteomyelitis, and imaging generators of musculoskeletal pain. Conclusion. Together, these applications suggest that next-generation musculoskeletal radiology will facilitate quantitative visualization of molecular and cellular biomarkers, an advancement that appeared futuristic just a decade ago. © American Roentgen Ray Society. |
| Keywords: | fracture; osteolysis; unclassified drug; review; disease marker; nuclear magnetic resonance imaging; positron emission tomography; biological markers; infection; pain; protein degradation; inflammation; immunoglobulin enhancer binding protein; molecular imaging; ultrasound; quantitative analysis; arthritis; fluorodeoxyglucose f 18; medronate technetium tc 99m; ciprofloxacin; bone; radiopharmaceutical agent; stem cells; imaging; nuclear medicine; rheumatoid arthritis; osteoarthritis; osteoclast; cell marker; macrophage; fluorine 18; single photon emission computer tomography; bone remodeling; bioluminescence; musculoskeletal disease; fluorescence imaging; diffusion of innovation; osteoblast; arthropathy; muscle; bone turnover; osteomyelitis; musculoskeletal diseases; musculoskeletal pain; cartilage; guanidine; tractography; ciprofloxacin tc 99m; chondrocyte; calcium channel; alafosfalin tc 99m; cefuroxime axetil tc 99m; saxitoxin f 18; water o 15; fluorescence reflectance imaging; musculoskeletal procedure; musculoskeletal radiology |
| Journal Title: | American Journal of Roentgenology |
| Volume: | 201 |
| Issue: | 2 |
| ISSN: | 0361-803X |
| Publisher: | American Roentgen Ray Society |
| Date Published: | 2013-08-01 |
| Start Page: | 264 |
| End Page: | 277 |
| Language: | English |
| DOI: | 10.2214/ajr.13.10713 |
| PROVIDER: | scopus |
| PUBMED: | 23795682 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 1 October 2013" - "CODEN: AJROA" - "Source: Scopus" |
