Prevalence of hematopoietic cell transplant survivors in the United States Journal Article


Authors: Majhail, N. S.; Tao, L.; Bredeson, C.; Davies, S.; Dehn, J.; Gajewski, J. L.; Hahn, T.; Jakubowski, A.; Joffe, S.; Lazarus, H. M.; Parsons, S. K.; Robien, K.; Lee, S. J.; Kuntz, K. M.
Article Title: Prevalence of hematopoietic cell transplant survivors in the United States
Abstract: Advances in hematopoietic cell transplantation (HCT) have led to an increasing number of transplant survivors. To adequately support their healthcare needs, there is a need to know the prevalence of HCT survivors. We used data on 170,628 recipients of autologous and allogeneic HCT reported to the Center for International Blood and Marrow Transplant Research from 1968 to 2009 to estimate the current and future number of HCT survivors in the United States. Stacked cohort simulation models were used to estimate the number of HCT survivors in the United States in 2009 and to make projections for HCT survivors by the year 2030. There were 108,900 (range, 100,500 to 115,200) HCT survivors in the United States in 2009. This included 67,000 autologous HCT and 41,900 allogeneic HCT survivors. The number of HCT survivors is estimated to increase by 2.5 times by the year 2020 (242,000 survivors) and 5 times by the year 2030 (502,000 survivors). By 2030, the age at transplant will be<18years for 14% of all survivors (n=64,000), 18 to 59years for 61% survivors (n=276,000), and 60years and older for 25% of survivors (n=113,000). In coming decades, a large number of individuals will be HCT survivors. Transplant center providers, hematologists, oncologists, primary care physicians, and other specialty providers will need to be familiar with the unique and complex health issues faced by this population. © 2013 American Society for Blood and Marrow Transplantation.
Keywords: adult; major clinical study; united states; multiple myeloma; prevalence; chronic myeloid leukemia; survivor; survivors; simulation; acute leukemia; myelodysplastic syndrome; lymphoma; allogeneic hematopoietic stem cell transplantation; general practitioner; autologous hematopoietic stem cell transplantation; hematopoietic cell transplantation; allogeneic; health care need; oncologist; autologous; hematologist
Journal Title: Biology of Blood and Marrow Transplantation
Volume: 19
Issue: 10
ISSN: 1083-8791
Publisher: Elsevier Inc.  
Date Published: 2013-10-01
Start Page: 1498
End Page: 1501
Language: English
DOI: 10.1016/j.bbmt.2013.07.020
PROVIDER: scopus
PMCID: PMC3779514
PUBMED: 23906634
DOI/URL:
Notes: --- - "Export Date: 1 October 2013" - "CODEN: BBMTF" - "Source: Scopus"
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