Is there a role for neoadjuvant chemotherapy without radiotherapy in locally advanced rectal cancer? Journal Article
| Authors: | Cercek, A.; Goodman, K. A. |
| Article Title: | Is there a role for neoadjuvant chemotherapy without radiotherapy in locally advanced rectal cancer? |
| Abstract: | The treatment paradigm for locally advanced rectal cancer is multidisciplinary and includes chemoradiotherapy and surgery followed by adjuvant chemotherapy. This review discusses the rationale behind multimodality treatment, the role of radiotherapy, and the potential for its omission in selected patients in the future. © 2013 Springer Science+Business Media New York. |
| Keywords: | cancer survival; overall survival; review; bevacizumab; fluorouracil; advanced cancer; drug efficacy; cancer radiotherapy; disease free survival; chemotherapy; quality of life; distant metastasis; infertility; postoperative complication; fibrosis; sexual dysfunction; folinic acid; adjuvant chemotherapy; oxaliplatin; rectum cancer; chemoradiotherapy; induction chemotherapy; rectal cancer; randomized controlled trial (topic); folfox; preoperative radiotherapy; bladder dysfunction; pelvic radiotherapy; locally advanced rectal cancer; long-term quality of life |
| Journal Title: | Current Colorectal Cancer Reports |
| Volume: | 9 |
| Issue: | 2 |
| ISSN: | 1556-3790 |
| Publisher: | Springer |
| Date Published: | 2013-01-01 |
| Start Page: | 126 |
| End Page: | 129 |
| Language: | English |
| DOI: | 10.1007/s11888-013-0171-8 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Export Date: 1 October 2013" - "Source: Scopus" |
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