Up and down or side to side? A systematic review and meta-analysis examining the impact of incision on outcomes after abdominal surgery Journal Article


Authors: Bickenbach, K. A.; Karanicolas, P. J.; Ammori, J. B.; Jayaraman, S.; Winter, J. M.; Fields, R. C.; Govindarajan, A.; Nir, I.; Rocha, F. G.; Brennan, M. F.
Article Title: Up and down or side to side? A systematic review and meta-analysis examining the impact of incision on outcomes after abdominal surgery
Abstract: Background: The aim of this study was to examine whether midline, paramedian, or transverse incisions offer potential advantages for abdominal surgery. Data Sources: We searched MEDLINE, Embase, Web of Science, and The Cochrane Central Register of Controlled Trials from 1966 to 2009 for randomized controlled trials comparing incision choice. Methods: We systematically assessed trials for eligibility and validity and extracted data in duplicate. We pooled data using a random-effects model. Results: Twenty-four studies were included. Transverse incisions required less narcotics than midline incisions (weighted mean difference = 23.4 mg morphine; 95% confidence interval [CI], 6.9 to 39.9) and resulted in a smaller change in the forced expiratory volume in 1 second on postoperative day 1 (weighted mean difference = -6.94%; 95% CI, -10.74 to -3.13). Midline incisions resulted in higher hernia rates compared with both transverse incisions (relative risk = 1.77; 95% CI, 1.09 to 2.87) and paramedian incisions (relative risk = 3.41; 95% CI, 1.02 to 11.45). Conclusions: Both transverse and paramedian incisions are associated with a lower hernia rate than midline incisions and should be considered when exposure is equivalent. © 2013 Elsevier Inc. All rights reserved.
Keywords: treatment outcome; postoperative period; laparotomy; bleeding; randomized controlled trials as topic; postoperative complication; postoperative complications; length of stay; pethidine; abdomen; systematic review; operation duration; hernia; gastrectomy; surgical procedures, operative; medline; validity; abdominal surgery; morphine; analgesics, opioid; cochrane library; cholecystectomy; forced expiratory volume; hemicolectomy; wound infection; postoperative pain; visual analog scale; wound dehiscence; wound complication; meta analysis; meta-analysis; embase; randomized controlled trial (topic); spirometry; incision; assisted ventilation; emergency surgery; hemia; midline incision; paramedian incision; transverse incision; ketobemidone; peritoneal dialysis; hernia, abdominal
Journal Title: American Journal of Surgery
Volume: 206
Issue: 3
ISSN: 0002-9610
Publisher: Elsevier Inc.  
Date Published: 2013-09-01
Start Page: 400
End Page: 409
Language: English
DOI: 10.1016/j.amjsurg.2012.11.008
PROVIDER: scopus
PUBMED: 23570737
DOI/URL:
Notes: --- - Cited By (since 1996):1 - "Export Date: 1 October 2013" - "CODEN: AJSUA" - "Source: Scopus"
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MSK Authors
  1. Murray F Brennan
    1059 Brennan
  2. Itzhak Nir
    1 Nir
  3. Flavio G Rocha
    12 Rocha
  4. Jordan Michael Winter
    9 Winter
  5. Ryan Courtney Fields
    19 Fields
  6. John Brian Ammori
    9 Ammori