Authors: | Ripley, R. T.; Rusch, V. W. |
Article Title: | Role of induction therapy. Surgical resection of non-small cell lung cancer after induction therapy |
Abstract: | Patients with Stage III non-small cell lung cancer are best managed by multimodality therapy. Patients with N2 disease can be treated with induction therapy (usually chemotherapy) followed by surgical resection. Patients whose medical comorbidities preclude surgery should be treated with definitive chemoradiotherapy. T3 or T4 tumors involving the superior sulcus or spine are best managed with induction chemoradiotherapy and surgical resection. © 2013 Elsevier Inc. |
Keywords: | cancer chemotherapy; cancer survival; cancer surgery; overall survival; review; cancer recurrence; cisplatin; cancer risk; multimodality cancer therapy; paclitaxel; cancer adjuvant therapy; cancer radiotherapy; disease free survival; combined modality therapy; neoadjuvant therapy; cancer staging; outcome assessment; positron emission tomography; sensitivity and specificity; carboplatin; progression free survival; multiple cycle treatment; lung non small cell cancer; lung resection; thoracotomy; carcinoma, non-small-cell lung; lung neoplasms; pneumonectomy; distant metastasis; vinblastine; comorbidity; gefitinib; surgery; surgical mortality; preoperative treatment; lung function; mitomycin; mediastinoscopy; fluorodeoxyglucose; chemoradiotherapy; induction chemotherapy; induction therapy; mediastinum lymph node; phase 2 clinical trial (topic); meta analysis (topic); phase 3 clinical trial (topic); endobronchial ultrasonography; pancoast tumor; long term survival; adjuvant chemoradiotherapy; chemoradiotherapy, adjuvant; stage iii lung cancer |
Journal Title: | Thoracic Surgery Clinics |
Volume: | 23 |
Issue: | 3 |
ISSN: | 1547-4127 |
Publisher: | W.B. Saunders Co-Elsevier Inc. |
Date Published: | 2013-08-01 |
Start Page: | 273 |
End Page: | 285 |
Language: | English |
DOI: | 10.1016/j.thorsurg.2013.04.004 |
PROVIDER: | scopus |
PUBMED: | 23931012 |
DOI/URL: | |
Notes: | --- - "Export Date: 4 September 2013" - "CODEN: TSCHC" - "Source: Scopus" |