Randomized clinical trials in gastrointestinal stromal tumors Journal Article
| Authors: | Learn, P. A.; Sicklick, J. K.; DeMatteo, R. P. |
| Article Title: | Randomized clinical trials in gastrointestinal stromal tumors |
| Abstract: | Gastrointestinal (GI) stromal tumor (GIST) is the most common mesenchymal tumor of the GI tract, constituting 80% of all GI mesenchymal tumors and approximately 20% of all small bowel malignancies, excluding lymphomas. This article provides a summary of recent randomized clinical trials of these tumors. © 2010 Elsevier Inc. All rights reserved. |
| Keywords: | cancer survival; treatment outcome; disease-free survival; clinical trial; drug tolerability; fatigue; review; cancer recurrence; doxorubicin; placebo; sunitinib; diarrhea; dose response; drug dose comparison; drug dose reduction; drug efficacy; drug safety; drug withdrawal; gastrointestinal hemorrhage; treatment duration; unspecified side effect; drug targeting; gemcitabine; cancer adjuvant therapy; cancer radiotherapy; temozolomide; drug megadose; cytoreductive surgery; gastrointestinal stromal tumor; imatinib; gastrointestinal stromal tumors; edema; low drug dose; quality of life; controlled clinical trial; etoposide; nausea; randomized controlled trial; randomized controlled trials as topic; antineoplastic activity; ifosfamide; cancer resistance; abdominal pain; drug dose escalation; drug hypersensitivity; hyperglycemia; dosage schedule comparison; long term care; skin discoloration; dermatitis; drug absorption; gastrointestinal surgery; drug treatment failure; drug protein binding; recurrence-free survival; abdominal bleeding; short course therapy |
| Journal Title: | Surgical Oncology Clinics of North America |
| Volume: | 19 |
| ISSN: | 1055-3207 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2010-01-01 |
| Start Page: | 101 |
| End Page: | 113 |
| Language: | English |
| DOI: | 10.1016/j.soc.2009.09.004 |
| PUBMED: | 19914562 |
| PROVIDER: | scopus |
| PMCID: | PMC3164338 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 20 April 2011" - "CODEN: SOCAF" - "Source: Scopus" |
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