Vaccinations for healthcare personnel: Update on influenza, hepatitis B, and pertussis Journal Article
| Authors: | Kaltsas, A.; Sepkowitz, K. |
| Article Title: | Vaccinations for healthcare personnel: Update on influenza, hepatitis B, and pertussis |
| Abstract: | PURPOSE OF REVIEW: Healthcare personnel (HCP) are at risk for exposure to and transmission of potentially life-threatening vaccine preventable diseases to patients and colleagues. The Centers for Disease Control and Advisory Committee on Immunization Practices (ACIP) recommend routine influenza immunization and maintenance of immunity to hepatitis B and pertussis, among others. In this article, we aim to review recently approved influenza vaccines, as well as address some of the issues regarding hepatitis B and pertussis vaccinations in HCP. RECENT FINDINGS: Several new formulations of influenza vaccines are now available, including quadrivalent vaccines and non-egg-based vaccines; their use in HCP requires further study. An alarming rise in pertussis rates has led to a revision of ACIP guidelines recommending vaccination for women during each pregnancy. Persistent lack of immunity to hepatitis B after vaccine series remains a problem for many HCP. SUMMARY: Inactivated trivalent influenza vaccines remain the safest and most widely studied influenza vaccinations for healthcare workers. A pertussis booster in the form of Tdap is now recommended for most HCP. More studies are needed regarding the issue of nonresponders in HCP who receive the three-dose hepatitis B vaccine series, as there are some promising strategies available that may boost immune responses. Copyright © Lippincott Williams & Wilkins. |
| Keywords: | unclassified drug; single nucleotide polymorphism; review; hepatitis; drug efficacy; hepatitis b; nonhuman; drug megadose; thrombocytopenia; herpes zoster; practice guideline; hospitalization; immune response; arthritis; immunogenicity; antibody response; vaccination; long term care; brain disease; peripheral edema; limb pain; limb swelling; health care personnel; hospital discharge; cd4 lymphocyte count; virus replication; hospital infection; encephalitis; hepatitis b vaccine; influenza vaccine; infection control; influenza; anaphylaxis; chickenpox vaccine; chickenpox; influenza, human; recombinant vaccine; infectious disease transmission, patient-to-professional; vaccines; diphtheria pertussis tetanus vaccine; live vaccine; meningococcus vaccine; pertussis vaccine; meningococcosis; pertussis; nose obstruction; diphtheria; immunization; tetanus; whooping cough; measles mumps rubella vaccine; inactivated vaccine; randomized controlled trial (topic); measles; mumps; rubella; seroconversion; systematic review (topic); virus shedding; rhinorrhea; seroprevalence; communicable disease control; influenza a; influenza b; healthcare workers; healthcare personnel; febrile convulsion; acellular vaccine; diphtheria toxoid; non egg based vaccine; post exposure prophylaxis; vaccine failure |
| Journal Title: | Current Opinion in Infectious Diseases |
| Volume: | 26 |
| Issue: | 4 |
| ISSN: | 0951-7375 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2013-08-01 |
| Start Page: | 366 |
| End Page: | 377 |
| Language: | English |
| DOI: | 10.1097/QCO.0b013e3283630ee5 |
| PROVIDER: | scopus |
| PUBMED: | 23806899 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 1 August 2013" - "CODEN: COIDE" - "Source: Scopus" |
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