Back to baseline: Erectile function recovery after radical prostatectomy from the patients' perspective Journal Article


Authors: Nelson, C. J.; Scardino, P. T.; Eastham, J. A.; Mulhall, J. P.
Article Title: Back to baseline: Erectile function recovery after radical prostatectomy from the patients' perspective
Abstract: Introduction: A variety of erectile function recovery (EFR) rates are reported post-radical prostatectomy (RP), with some suggesting EFR rates over 90% [1]. Clinical experience suggests that patients view EFR as getting back to their baseline (BTB) erectile functioning (EF) without the use of medication. Aim: This study explores EFR defined as BTB. Method: Men pre-RP and 24 months post-RP completed the Erectile Function Domain (EFD) of the International Index of Erectile Function and one question on phosphodiesterase type 5 inhibitor (PDE5i) use. Men using a PDE5i at baseline were excluded. Main Outcome Measures: At 24m, "back to baseline" was defined as achieving the baseline EFD score (within 1 point or higher). Analyses included descriptive statistics, chi-square, and logistic regression. Results: One hundred eighty men had an average age at RP of 59 (SD=7) years. When including men who were using a PDE5i at 24 months, 43% (N=78, 95% CI: 36-51%) returned BTB. When considering BTB without the use of a PDE5i, 22% (N=39, 95% CI: 16% to 28%) returned BTB. When focusing on a subset of men with baseline EFD≥24 (N=132), 36% (N=47, 95% CI: 28% to 44%) returned BTB at 24 months using a PDE5i and 16% (N=21, 95% CI: 11% to 23%) without the use of a PDE5i. For this group, there was a significant difference by age (<60 years, 23% vs. ≥60 years, 4%, P<0.001), which remained a significant predictor (OR=6.25, 95% CI: 1.88 to 50, P<0.001) in multivariable analysis. Conclusions: Twenty-two percent of the entire sample and 16% of the men with functional (EFD≥24) baseline erections returned to BTB EF without the use of medication. Only 4% of men who were ≥60 years old with functional erections pre-surgery achieved BTB EF. Although gaining partial EF is also important, men pre-RP should be educated on EFR and the chance of "back to baseline" EF. © 2013 International Society for Sexual Medicine.
Keywords: prostate cancer; erectile dysfunction; sexual function; pre-operative erectile function
Journal Title: Journal of Sexual Medicine
Volume: 10
Issue: 6
ISSN: 1743-6095
Publisher: Elsevier Inc.  
Date Published: 2013-06-01
Start Page: 1636
End Page: 1643
Language: English
DOI: 10.1111/jsm.12135
PROVIDER: scopus
PUBMED: 23551767
PMCID: PMC4742368
DOI/URL:
Notes: - "Export Date: 1 July 2013" - "Source: Scopus"
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  1. Peter T Scardino
    671 Scardino
  2. John P Mulhall
    601 Mulhall
  3. James Eastham
    537 Eastham
  4. Christian Nelson
    391 Nelson