Confocal microscopy to guide laser ablation of basal cell carcinoma: A preliminary feasibility study Conference Paper


Authors: Larson, B. A.; Sierra, H.; Chen, J.; Rajadhyaksha, M.
Title: Confocal microscopy to guide laser ablation of basal cell carcinoma: A preliminary feasibility study
Conference Title: Photonic Therapeutics and Diagnostics IX
Abstract: Laser ablation may be a promising method for removal of skin lesions, with the potential for better cosmetic outcomes and reduced scarring and infection. An obstacle to implementing laser ablation is that the treatment leaves no tissue for histopathological analysis. Pre-operative and intra-operative mapping of BCCs using confocal microscopy may guide the ablation of the tumor until all tumor is removed. We demonstrate preliminary feasibility of confocal microscopy to guide laser ablation of BCCs in freshly excised tissue from Mohs surgery. A 2940 nm Er:YAG laser provides efficient ablation of tumor with reduced thermal damage to the surrounding tissue. © 2013 SPIE.
Keywords: basal cell carcinoma; confocal microscopy; tumors; feasibility studies; mohs surgery; intra-operative; ablation; thermal damage; laser ablation; bcc; er:yag lasers; histopathological analysis
Journal Title Proceedings of SPIE
Volume: 8565
Conference Dates: 2013 Feb 2
Conference Location: San Francisco, CA
ISBN: 0277-786X
Publisher: SPIE  
Location: San Francisco, CA
Date Published: 2013-01-01
Start Page: 856502
Language: English
PROVIDER: scopus
DOI: 10.1117/12.2005482
DOI/URL:
Notes: --- - Progress in Biomedical Optics and Imaging - Proceedings of SPIE - Progr. Biomed. Opt. Imaging Proc. SPIE - "Conference code: 97149" - "Export Date: 1 July 2013" - ":doi 10.1117/12.2005482" - "Sponsors: The Society of Photo-Optical Instrumentation Engineers (SPIE)" - 2 February 2013 through 7 February 2013 - "Source: Scopus"
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  1. Chih-Shan Jason Chen
    55 Chen