Authors: | Goldlust, S. A.; Graber, J. J.; Bossert, D. F.; Avila, E. K. |
Article Title: | Headache in patients with cancer |
Abstract: | Contemporary cancer research has led to unparalleled advances in therapeutics and improved survival. Even as treatment options continue to improve, quality of life should remain a priority. Headache drastically impacts the quality of life of patients with cancer and has a wide etiological scope, making diagnosis a challenge. Intracranial mass lesions are only one cause; others include extracranial tumors, paraneoplastic processes, and the consequences of diagnostic and therapeutic interventions used in cancer care. Fortunately, cancer-related headache is treatable, but a sound understanding of the variable etiologies is crucial to appropriate diagnostic evaluation and treatment. In this review, we highlight the important causes of headache in the patient with cancer, and consider the epidemiology, pathophysiology, clinical course, and treatment options for each. © 2010 Springer Science+Business Media, LLC. |
Keywords: | vasculotropin; cancer chemotherapy; leukemia; antibiotic agent; cancer surgery; fludarabine; thalidomide; clinical feature; disease course; review; postoperative period; bevacizumab; pathophysiology; cancer patient; cancer radiotherapy; rituximab; temozolomide; topotecan; neuroimaging; nuclear magnetic resonance imaging; brain tumor; neoplasm; neoplasms; imatinib; disease association; unindexed drug; melanoma; quality of life; pain; erythropoietin; opiate; dexamethasone; vincristine; drug potency; cetuximab; monoclonal antibody; lung tumor; nonhodgkin lymphoma; cerebrospinal fluid; lumbar puncture; early diagnosis; vein thrombosis; nonsteroid antiinflammatory agent; brain disease; tamoxifen; antihypertensive agent; progressive multifocal leukoencephalopathy; octreotide; headache; immunomodulating agent; drug half life; anticonvulsive agent; corticosteroid; trastuzumab; cerebrospinal fluid analysis; hormonal regulation; shunting; mediastinum tumor; retinoic acid; disease exacerbation; head and neck tumor; alemtuzumab; cranial neuropathy; skull tumor; meningeal metastasis; anticoagulant agent; intracranial tumor; cimetidine; central nervous system disease; thrombectomy; central nervous system infection; ergot alkaloid; methylxanthine; cerebrospinal fluid shunting; demyelination; hypophysis tumor; posterior reversible encephalopathy syndrome |
Journal Title: | Current Pain and Headache Reports |
Volume: | 14 |
Issue: | 6 |
ISSN: | 1531-3433 |
Publisher: | Springer |
Date Published: | 2010-12-01 |
Start Page: | 455 |
End Page: | 464 |
Language: | English |
DOI: | 10.1007/s11916-010-0153-3 |
PUBMED: | 20927609 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Export Date: 20 April 2011" - "CODEN: CPHRG" - "Source: Scopus" |