Headache in patients with cancer Journal Article


Authors: Goldlust, S. A.; Graber, J. J.; Bossert, D. F.; Avila, E. K.
Article Title: Headache in patients with cancer
Abstract: Contemporary cancer research has led to unparalleled advances in therapeutics and improved survival. Even as treatment options continue to improve, quality of life should remain a priority. Headache drastically impacts the quality of life of patients with cancer and has a wide etiological scope, making diagnosis a challenge. Intracranial mass lesions are only one cause; others include extracranial tumors, paraneoplastic processes, and the consequences of diagnostic and therapeutic interventions used in cancer care. Fortunately, cancer-related headache is treatable, but a sound understanding of the variable etiologies is crucial to appropriate diagnostic evaluation and treatment. In this review, we highlight the important causes of headache in the patient with cancer, and consider the epidemiology, pathophysiology, clinical course, and treatment options for each. © 2010 Springer Science+Business Media, LLC.
Keywords: vasculotropin; cancer chemotherapy; leukemia; antibiotic agent; cancer surgery; fludarabine; thalidomide; clinical feature; disease course; review; postoperative period; bevacizumab; pathophysiology; cancer patient; cancer radiotherapy; rituximab; temozolomide; topotecan; neuroimaging; nuclear magnetic resonance imaging; brain tumor; neoplasm; neoplasms; imatinib; disease association; unindexed drug; melanoma; quality of life; pain; erythropoietin; opiate; dexamethasone; vincristine; drug potency; cetuximab; monoclonal antibody; lung tumor; nonhodgkin lymphoma; cerebrospinal fluid; lumbar puncture; early diagnosis; vein thrombosis; nonsteroid antiinflammatory agent; brain disease; tamoxifen; antihypertensive agent; progressive multifocal leukoencephalopathy; octreotide; headache; immunomodulating agent; drug half life; anticonvulsive agent; corticosteroid; trastuzumab; cerebrospinal fluid analysis; hormonal regulation; shunting; mediastinum tumor; retinoic acid; disease exacerbation; head and neck tumor; alemtuzumab; cranial neuropathy; skull tumor; meningeal metastasis; anticoagulant agent; intracranial tumor; cimetidine; central nervous system disease; thrombectomy; central nervous system infection; ergot alkaloid; methylxanthine; cerebrospinal fluid shunting; demyelination; hypophysis tumor; posterior reversible encephalopathy syndrome
Journal Title: Current Pain and Headache Reports
Volume: 14
Issue: 6
ISSN: 1531-3433
Publisher: Springer  
Date Published: 2010-12-01
Start Page: 455
End Page: 464
Language: English
DOI: 10.1007/s11916-010-0153-3
PUBMED: 20927609
PROVIDER: scopus
DOI/URL:
Notes: --- - "Export Date: 20 April 2011" - "CODEN: CPHRG" - "Source: Scopus"
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  1. Jerome Jeffrey Graber
    24 Graber
  2. Edward Kenneth Avila
    37 Avila
  3. Dana F Bossert
    13 Bossert