Pathophysiology and management of thrombosis in cancer: 150 years of progress Journal Article
| Author: | Soff, G. A. |
| Article Title: | Pathophysiology and management of thrombosis in cancer: 150 years of progress |
| Abstract: | The association of thrombosis with cancer has been recognized since the middle of the nineteenth century. It remains a common and serious complication of the cancer itself, as well as chemotherapy. Thrombosis is the second leading cause of death in cancer patients, second only to the cancer itself. For many years the treatment options for managing thrombosis in cancer had been static, but the past decade has seen significant evolution in the management, with the clear superiority of low molecular weight heparin over warfarin for secondary prevention of thrombosis. This article will review the understanding and management of thrombosis in cancer. © 2013 Springer Science+Business Media New York. |
| Keywords: | placebo; drug dose reduction; conference paper; pathophysiology; neoplasm; neoplasms; animals; bleeding; thrombocytopenia; history, 21st century; lung embolism; history, 20th century; oncogene; tumor suppressor gene; thrombosis; cancer cell; history, 19th century; anticoagulants; warfarin; heparin; drug substitution; heart atrium fibrillation; heparin induced thrombocytopenia; enoxaparin; thrombocyte transfusion; low molecular weight heparin; venous thromboembolism; anticoagulant agent; apixaban; dalteparin; rivaroxaban; thromboplastin; blood clotting; clinical trial (topic); heparin, low-molecular-weight; blood clotting factor 10a inhibitor; thrombosis prevention; dabigatran; antivitamin k; disseminated intravascular clotting; semuloparin; membrane microparticle |
| Journal Title: | Journal of Thrombosis and Thrombolysis |
| Volume: | 35 |
| Issue: | 3 |
| ISSN: | 0929-5305 |
| Publisher: | Springer |
| Date Published: | 2013-04-01 |
| Start Page: | 346 |
| End Page: | 351 |
| Language: | English |
| DOI: | 10.1007/s11239-013-0897-9 |
| PROVIDER: | scopus |
| PUBMED: | 23440574 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 3 June 2013" - "CODEN: JTTHF" - "Source: Scopus" |
