Transforming epidemiology for 21st century medicine and public health Journal Article


Authors: Khoury, M. J.; Lam, T. K.; Ioannidis, J. P. A.; Hartge, P.; Spitz, M. R.; Buring, J. E.; Chanock, S. J.; Croyle, R. T.; Goddard, K. A.; Ginsburg, G. S.; Herceg, Z.; Hiatt, R. A.; Hoover, R. N.; Hunter, D. J.; Kramer, B. S.; Lauer, M. S.; Meyerhardt, J. A.; Olopade, O. I.; Palmer, J. R.; Sellers, T. A.; Seminara, D.; Ransohoff, D. F.; Rebbeck, T. R.; Tourassi, G.; Winn, D. M.; Zauber, A.; Schully, S. D.
Article Title: Transforming epidemiology for 21st century medicine and public health
Abstract: In 2012, the National Cancer Institute (NCI) engaged the scientific community to provide a vision for cancer epidemiology in the 21st century. Eight overarching thematic recommendations, with proposed corresponding actions for consideration by funding agencies, professional societies, and the research community emerged from the collective intellectual discourse. The themes are (i) extending the reach of epidemiology beyond discovery and etiologic research to include multilevel analysis, intervention evaluation, implementation, and outcomes research; (ii) transforming the practice of epidemiology by moving toward more access and sharing of protocols, data, metadata, and specimens to foster collaboration, to ensure reproducibility and replication, and accelerate translation; (iii) expanding cohort studies to collect exposure, clinical, and other information across the life course and examining multiple health-related endpoints; (iv) developing and validating reliable methods and technologies to quantify exposures and outcomes on a massive scale, and to assess concomitantly the role of multiple factors in complex diseases; (v) integrating "big data" science into the practice of epidemiology; (vi) expanding knowledge integration to drive research, policy, and practice; (vii) transforming training of 21st century epidemiologists to address interdisciplinary and translational research; and (viii) optimizing the use of resources and infrastructure for epidemiologic studies. These recommendations can transform cancer epidemiology and the field of epidemiology, in general, by enhancing transparency, interdisciplinary collaboration, and strategic applications of new technologies. They should lay a strong scientific foundation for accelerated translation of scientific discoveries into individual and population health benefits. © 2013 American Association for Cancer Research.
Keywords: united states; neoplasms; reproducibility; biomedical research; history, 21st century; health care policy; medical information; medical research; public health; medical society; medical oncology; outcomes research; cancer epidemiology; national cancer institute (u.s.); translational research; guidelines as topic; epidemiologic studies
Journal Title: Cancer Epidemiology Biomarkers and Prevention
Volume: 22
Issue: 4
ISSN: 1055-9965
Publisher: American Association for Cancer Research  
Date Published: 2013-04-01
Start Page: 508
End Page: 516
Language: English
DOI: 10.1158/1055-9965.epi-13-0146
PROVIDER: scopus
PMCID: PMC3625652
PUBMED: 23462917
DOI/URL:
Notes: --- - Cited By (since 1996):1 - "Export Date: 3 June 2013" - "CODEN: CEBPE" - "Source: Scopus"
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Ann G Zauber
    314 Zauber