Induction chemotherapy in the management of head and neck cancer Journal Article


Authors: Fury, M. G.; Shah, J. P.
Article Title: Induction chemotherapy in the management of head and neck cancer
Abstract: The strategy of induction chemotherapy prior to planned definitive local therapy for head and neck squamous cell carcinoma has been studied for over 30 years, and appears to have a role in select clinical situations. Here we review landmark studies regarding induction chemotherapy, both in the pre-taxane era and in the current taxane era, and we address some of the unresolved questions regarding the role of induction chemotherapy in head and neck cancer. © 2010 Wiley-Liss, Inc.
Keywords: cancer chemotherapy; cancer survival; treatment response; cancer surgery; clinical trial; drug tolerability; review; larynx carcinoma; squamous cell carcinoma; carcinoma, squamous cell; cisplatin; fluorouracil; drug efficacy; patient selection; treatment planning; antineoplastic agents; paclitaxel; cancer radiotherapy; chemotherapy, adjuvant; neoadjuvant therapy; cancer staging; carboplatin; multiple cycle treatment; nephrotoxicity; bone marrow suppression; cetuximab; docetaxel; febrile neutropenia; rash; add on therapy; head and neck cancer; head and neck neoplasms; bleomycin; nausea and vomiting; oropharynx cancer; organ preservation; medical literature; taxoids; taxane derivative; drug substitution; larynx cancer; everolimus; mouth cancer; oropharynx carcinoma; induction chemotherapy; hypopharynx cancer; bridged compounds
Journal Title: Journal of Surgical Oncology
Volume: 101
Issue: 4
ISSN: 0022-4790
Publisher: Wiley Blackwell  
Date Published: 2010-03-15
Start Page: 292
End Page: 298
Language: English
DOI: 10.1002/jso.21438
PUBMED: 20187068
PROVIDER: scopus
DOI/URL:
Notes: --- - "Export Date: 20 April 2011" - "CODEN: JSONA" - "Source: Scopus"
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  1. Matthew G Fury
    102 Fury
  2. Jatin P Shah
    721 Shah