Authors: | Beaulieu, A. M.; Bezman, N. A.; Lee, J. E.; Matloubian, M.; Sun, J. C.; Lanier, L. L. |
Article Title: | MicroRNA function in NK-cell biology |
Abstract: | The important role of microRNAs in directing immune responses has become increasingly clear. Here, we highlight discoveries uncovering the role of specific microRNAs in regulating the development and function of natural killer (NK) cells. Furthermore, we discuss the impact of NK cells on the entire immune system during global and specific microRNA ablation in the settings of inflammation, infection, and immune dysregulation. © 2013 John Wiley & Sons A/S. |
Keywords: | nonhuman; neoplasms; cd8 antigen; cd8+ t lymphocyte; t lymphocyte; animals; microrna; inflammation; rna interference; cell differentiation; cytotoxicity; b lymphocyte; natural killer cell; killer cells, natural; cytotoxicity, immunologic; immunomodulation; development; virus infection; micrornas; homeostasis; nk; immune dysregulation; natural killer; immune system diseases |
Journal Title: | Immunological Reviews |
Volume: | 253 |
Issue: | 1 |
ISSN: | 0105-2896 |
Publisher: | Wiley Blackwell |
Date Published: | 2013-05-01 |
Start Page: | 40 |
End Page: | 52 |
Language: | English |
PROVIDER: | scopus |
PMCID: | PMC3621029 |
PUBMED: | 23550637 |
DOI: | 10.1111/imr.12045 |
DOI/URL: | |
Notes: | --- - Cited By (since 1996):1 - "Export Date: 1 May 2013" - "CODEN: IMRED" - ":doi 10.1111/imr.12045" - "Source: Scopus" |