Cryoablation: Mechanism of action and devices Journal Article
| Authors: | Erinjeri, J. P.; Clark, T. W. I. |
| Article Title: | Cryoablation: Mechanism of action and devices |
| Abstract: | Cryoablation refers to all methods of destroying tissue by freezing. Cryoablation causes cellular damage, death, and necrosis of tissues by direct mechanisms, which cause cold-induced injury to cells, and indirect mechanisms, which cause changes to the cellular microenvironment and impair tissue viability. Cellular injury, both indirect and direct, can be influenced by four factors: cooling rate, target temperature, time at target temperature, and thawing rate. In this review, the authors describe the mechanisms of cellular injury that occur with cryoablation, the major advantages and disadvantages of cryoablation compared with other thermal ablation techniques, and the current commercially available cryoablation ablation systems. © 2010 SIR. |
| Keywords: | treatment outcome; review; neoplasms; apoptosis; cold injury; risk factor; medical instrumentation; thawing; ischemia; thrombosis; cell damage; thermodynamics; equipment design; cryoablation; temperature sensitivity; tissue repair; cryosurgery; tissue necrosis |
| Journal Title: | Journal of Vascular and Interventional Radiology |
| Volume: | 21 |
| Issue: | 8 Suppl. |
| ISSN: | 1051-0443 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2010-08-01 |
| Start Page: | S187 |
| End Page: | S191 |
| Language: | English |
| DOI: | 10.1016/j.jvir.2009.12.403 |
| PUBMED: | 20656228 |
| PROVIDER: | scopus |
| PMCID: | PMC6661161 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 1" - "Export Date: 20 April 2011" - "CODEN: JVIRE" - "Source: Scopus" |
