Platypnea-orthodeoxia syndrome: A diagnostic challenge Journal Article
| Authors: | Desouza, K. A.; Saraswat, S.; Desouza, S. A.; Rajaram, V.; Reddy, P. C.; Mosley, L.; Tandon, N. |
| Article Title: | Platypnea-orthodeoxia syndrome: A diagnostic challenge |
| Abstract: | Platypnea-orthodeoxia (P-O) syndrome is an underdiagnosed condition characterized by dyspnea and deoxygenation accompanying a change from a recumbent to an upright position. It is caused by increased right-to-left shunting of blood on assuming an upright position. The diagnosis of this shunt is often challenging. A case where a diagnosis was missed despite performing a tilt transesophageal echocardiogram with bubble study and a technetium labeled macroaggregated albumin scan is presented. However, a large patent foramen ovale (PFO) was found on autopsy. A brief overview of the diagnostic workup and management of this condition along with methods to increase the sensitivity of diagnostic tests is discussed. Copyright © 2009 by The Southern Medical Association. |
| Keywords: | aged; aged, 80 and over; case report; technetium 99m; sensitivity analysis; oxygen; dyspnea; hospitalization; syndrome; diagnostic test; autopsy; echocardiography; contrast echocardiography; hepatopulmonary syndrome; orthodeoxia; patent foramen ovale; platypnea; macrosalb tc 99m; arterial gas; deoxygenation; forced expiratory volume; oxygen breathing; platypnea orthodeoxia syndrome; pressure; shunting; spirography; standing; transesophageal echocardiography; valsalva maneuver; fatal outcome; foramen ovale, patent; oximetry; posture; serum albumin, radio-iodinated |
| Journal Title: | Southern Medical Journal |
| Volume: | 102 |
| Issue: | 10 |
| ISSN: | 0038-4348 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2009-10-01 |
| Start Page: | 1046 |
| End Page: | 1048 |
| Language: | English |
| DOI: | 10.1097/SMJ.0b013e3181b35f0f |
| PUBMED: | 19738537 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 1" - "Export Date: 30 November 2010" - "CODEN: SMJOA" - "Source: Scopus" |
