Endoscopic biopsy for tumors of the third ventricle Journal Article

Authors: Souweidane, M. M.; Sandberg, D. I.; Bilsky, M. H.; Gutin, P. H.
Article Title: Endoscopic biopsy for tumors of the third ventricle
Abstract: Twelve patients underwent endoscopic biopsy of a tumor involving the third ventricle. Nine patients had no significant medical history while 3 had a history of cancer. Unique characteristics of each case dictated the optimal surgical technique. Endoscopic tumor biopsy was combined with additional procedures in 9 cases; shunt insertion (3), shunt insertion with endoscopic septostomy (5), and transcallosal craniotomy (1). Diagnosis was established in 11 patients (92%); 6 primary brain tumors, 3 metastatic central nervous system tumors, 1 metastatic systemic cancer, and 1 region of post-treatment gliosis. One case was aborted due to poor visualization. Therapy was directly influenced by endoscopic biopsy in 11/12 cases (92%) and craniotomy for tumor resection was avoided in 10/12 patients (83%). Of the 5 patients who underwent endoscopic septostomy, 4 required no subsequent procedures for hydrocephalus. There were no complications, and hospital stay averaged 1.78 days for patients who underwent successful endoscopic biopsy. Tumors of the third ventricle are amenable to endoscopic biopsy with excellent diagnostic yield and low morbidity. The procedure must be tailored depending upon the tumor location within the third ventricle, the degree of ventriculomegaly, and the need to perform a septostomy. Singularly or combined with other endoscopic procedures, patients can be spared multiple and more invasive surgical procedures. Copyright (C) 2000 S. Karger AG, Basel.
Keywords: adolescent; adult; child; clinical article; controlled study; human tissue; treatment outcome; aged; child, preschool; middle aged; survival analysis; surgical technique; retrospective studies; clinical trial; brain tumor; glioma; diagnostic accuracy; tumor localization; melanoma; controlled clinical trial; diagnosis, differential; morbidity; gliosis; biopsy; postoperative complication; hospitalization; diagnostic value; craniotomy; endoscopic biopsy; shunting; endoscopy; neurosurgical procedures; hydrocephalus; brain ventricle tumor; brain third ventricle; cerebral ventricle neoplasms; third ventricle; endoscope; humans; human; male; female; priority journal; article
Journal Title: Pediatric Neurosurgery
Volume: 33
Issue: 3
ISSN: 1016-2291
Publisher: Karger  
Date Published: 2000-09-01
Start Page: 132
End Page: 137
Language: English
PUBMED: 11096360
PROVIDER: scopus
DOI: 10.1159/000028994
Notes: Export Date: 18 November 2015 -- Source: Scopus
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MSK Authors
  1. Mark H Bilsky
    222 Bilsky
  2. Philip H Gutin
    152 Gutin