Management options, survivorship, and emerging treatment strategies for follicular and Hodgkin lymphomas Journal Article
| Authors: | Czuczman, M.; Straus, D.; Gribben, J.; Bredenfeld, H.; Friedberg, J.; Bollard, C. |
| Article Title: | Management options, survivorship, and emerging treatment strategies for follicular and Hodgkin lymphomas |
| Abstract: | Our understanding of the biology underlying lymphoma is continually increasing and leading to improved treatment strategies for affected patients. However, clinical approaches differ between disease subtypes based on the likelihood of achieving durable remissions. For example, follicular lymphoma (FL) is a common and indolent form of non-Hodgkin lymphoma, in which most patients relapse after treatment and periods of remission become progressively shorter after each course of treatment. Thus, the main focus of research efforts in FL is to develop improved treatment strategies that provide prolonged periods of disease remission. In contrast, Hodgkin lymphoma (HL), although rare, is considered to be highly curable with current treatments and the clinical need is for effective-management strategies, potentially avoiding chemotherapy, that reduce long-term toxicity and improve quality of life for patients. This report summarizes the latest advances in our understanding of FL and HL, and demonstrates the different approaches required when developing novel treatment strategies for the two diseases. © 2010 Informa UK, Ltd. |
| Keywords: | cancer chemotherapy; cancer survival; treatment response; survival rate; fludarabine; prednisone; clinical trial; review; doxorubicin; cancer combination chemotherapy; cancer growth; drug efficacy; monotherapy; antineoplastic agents; ibritumomab tiuxetan; rituximab; antineoplastic agent; t lymphocyte; dacarbazine; quality of life; cyclophosphamide; vincristine; tumor biopsy; cancer mortality; vinblastine; hodgkin disease; cd20 antigen; cancer regression; cardiovascular risk; survivorship; remission induction; bleomycin; osteoporosis; large cell lymphoma; disease management; heart arrhythmia; cancer control; radioimmunotherapy; follicular lymphoma; lymphoma, follicular; ethnicity; chlorambucil; cell transplantation; cardiomyopathy; hodgkin lymphoma; female infertility; cladribine; azoospermia; autonomic dysfunction; chronic fatigue syndrome; pericardial disease; rheumatic heart disease |
| Journal Title: | Leukemia and Lymphoma |
| Volume: | 51 |
| Issue: | Suppl. |
| ISSN: | 1042-8194 |
| Publisher: | Taylor & Francis Group |
| Date Published: | 2010-08-01 |
| Start Page: | 41 |
| End Page: | 49 |
| Language: | English |
| DOI: | 10.3109/10428194.2010.500083 |
| PUBMED: | 20658953 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Export Date: 20 April 2011" - "CODEN: LELYE" - "Source: Scopus" |
