Genomic Dysregulation in gastric tumors Journal Article


Authors: Janjigian, Y. Y.; Kelsen, D. P.
Article Title: Genomic Dysregulation in gastric tumors
Abstract: Gastric cancer is among the most common human malignancies and the second leading cause of cancer-related death. The different epidemiologic and histopathology of subtypes of gastric cancer are associated with different genomic patterns. Data suggests that gene expression patterns of proximal, distal gastric cancers-intestinal type, and diffuse/signet cell are well separated. This review summarizes the genetic and epigenetic changes thought to drive gastric cancer and the emerging paradigm of gastric cancer as three unique disease subtypes. © 2012 Wiley Periodicals, Inc. Copyright © 2012 Wiley Periodicals, Inc.
Keywords: tumor marker; targeted therapy; gastric cancer; genomic analysis
Journal Title: Journal of Surgical Oncology
Volume: 107
Issue: 3
ISSN: 0022-4790
Publisher: Wiley Blackwell  
Date Published: 2013-03-01
Start Page: 237
End Page: 242
Language: English
DOI: 10.1002/jso.23263
PROVIDER: scopus
PUBMED: 23042588
DOI/URL:
Notes: --- - "Export Date: 1 March 2013" - "CODEN: JSONA" - "Source: Scopus"
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  1. Yelena Yuriy Janjigian
    394 Janjigian
  2. David P Kelsen
    537 Kelsen