Physical activity reduces risk for colon polyps in a multiethnic colorectal cancer screening population Journal Article

Authors: Sanchez, N. F.; Stierman, B.; Saab, S.; Mahajan, D.; Yeung, H.; Francois, F.
Article Title: Physical activity reduces risk for colon polyps in a multiethnic colorectal cancer screening population
Abstract: Background: Identifying modifiable factors that influence the epidemiology of colorectal cancer incidence among multiethnic groups might be informative for the development of public health strategies targeting the disease. Minimal data exists describing the impact of physical activity on colorectal polyp risk in United States minority populations. The aim of this study is to evaluate the relationship of exercise on the prevalence of polyps in a multiethnic colorectal cancer screening population. Results: We enrolled 982 patients: 558 Hispanic, 202 Asian,149 Black, and 69 White. Patients who reported exercising one or more hours weekly had a lower prevalence of any polyps (25.3% vs 33.2%, P = 0.008) as well as adenomas (13.8 vs. 18.9%, P = 0.03) compared to those who did not exercise. Black and Hispanic patients and those who were overweight or obese also had lower prevalence of polyps if they led an active lifestyle. Multivariate analysis revealed that age >55, male sex, and Black race/ethnicity were positively associated with the presence of adenomas, while a history of exercising one hour or more weekly was an independent negative predictor for the presence of adenomas anywhere in the colon (OR 0.67; 95% CI 0.4 - 0.9, P = 0.03). Conclusions: Exercising one hour per week was associated with a lower prevalence of polyps and adenomas when compared to those who exercised less or not at all. An active lifestyle provides benefits to groups who are at risk for colorectal cancer, such as Blacks. It also provides significant protection to overweight and obese individuals. Public health initiatives should promote physical activity as a cancer prevention tool in multiethnic populations. © 2012 Sanchez et al.; licensee BioMed Central Ltd.
Keywords: middle aged; united states; comparative study; methodology; prospective study; prospective studies; statistics; logistic models; prevalence; odds ratio; risk factors; exercise; obesity; overweight; mass screening; age factors; risk factor; age; risk assessment; risk; colorectal neoplasms; adenoma; colonoscopy; colorectal tumor; new york city; chi-square distribution; multivariate analysis; sex difference; physical activity; health; sex factors; risk reduction; african americans; european continental ancestry group; statistical model; ethnic group; colon polyp; colonic polyps; african american; risk reduction behavior; caucasian; hispanic; asian american; chi square distribution; ethnic groups; hispanic americans; ethnology; bmi; asian americans; colorectal polyps; urban health
Journal Title: BMC Research Notes
Volume: 5
ISSN: 1756-0500
Publisher: Biomed Central Ltd  
Date Published: 2012-06-01
Start Page: 312
Language: English
DOI: 10.1186/1756-0500-5-312
PUBMED: 22715975
PROVIDER: scopus
PMCID: PMC3437999
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 14 February 2013" - "Source: Scopus"
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