MRI perfusion in determining pseudoprogression in patients with glioblastoma Journal Article
| Authors: | Young, R. J.; Gupta, A.; Shah, A. D.; Graber, J. J.; Chan, T. A.; Zhang, Z.; Shi, W.; Beal, K.; Omuro, A. M. |
| Article Title: | MRI perfusion in determining pseudoprogression in patients with glioblastoma |
| Abstract: | We examine the role of dynamic susceptibility contrast (DSC) magnetic resonance imaging (MRI) perfusion in differentiating pseudoprogression from progression in 20 consecutive patients with treated glioblastoma. MRI perfusion was performed, and relative cerebral blood volume (rCBV), relative peak height (rPH), and percent signal recovery (PSR) were measured. Pseudoprogression demonstrated lower median rCBV (P=009) and rPH (P<.001), and higher PSR (P=039) than progression. DSC MRI perfusion successfully identified pseudoprogression in patients who did not require a change in treatment despite radiographic worsening following chemoradiotherapy. © 2013 Elsevier Inc. |
| Keywords: | glioblastoma; progression; pseudoprogression; mri perfusion |
| Journal Title: | Clinical Imaging |
| Volume: | 37 |
| Issue: | 1 |
| ISSN: | 0899-7071 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2013-01-01 |
| Start Page: | 41 |
| End Page: | 49 |
| Language: | English |
| DOI: | 10.1016/j.clinimag.2012.02.016 |
| PROVIDER: | scopus |
| PUBMED: | 23151413 |
| PMCID: | PMC4755513 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 1 February 2013" - "CODEN: CLIME" - "Source: Scopus" |
