Authors: | Kang, J. W.; Nguyen, F. T.; Lue, N.; Dasari, R. R.; Heller, D. A. |
Article Title: | Measuring uptake dynamics of multiple identifiable carbon nanotube species via high-speed confocal Raman imaging of live cells |
Abstract: | Carbon nanotube uptake was measured via high-speed confocal Raman imaging in live cells. Spatial and temporal tracking of two cell-intrinsic and nine nanotube-derived Raman bands was conducted simultaneously in RAW 264.7 macrophages. Movies resolved single (n, m) species, defects, and aggregation states of nanotubes transiently as well as the cell position, denoted by lipid and protein signals. This work portends the real-time molecular imaging of live cells and tissues using Raman spectroscopy, affording multiplexing and complete photostability. © 2012 American Chemical Society. |
Keywords: | molecular probe; intracellular trafficking; raman spectroscopy; raman microscopy; resonance raman scattering; single-walled carbon nanotube |
Journal Title: | Nano Letters |
Volume: | 12 |
Issue: | 12 |
ISSN: | 1530-6984 |
Publisher: | American Chemical Society |
Date Published: | 2012-12-12 |
Start Page: | 6170 |
End Page: | 6174 |
Language: | English |
DOI: | 10.1021/nl302991y |
PROVIDER: | scopus |
PUBMED: | 23151070 |
PMCID: | PMC3561480 |
DOI/URL: | |
Notes: | --- - "Export Date: 2 January 2013" - "CODEN: NALEF" - "Source: Scopus" |