Measuring uptake dynamics of multiple identifiable carbon nanotube species via high-speed confocal Raman imaging of live cells Journal Article


Authors: Kang, J. W.; Nguyen, F. T.; Lue, N.; Dasari, R. R.; Heller, D. A.
Article Title: Measuring uptake dynamics of multiple identifiable carbon nanotube species via high-speed confocal Raman imaging of live cells
Abstract: Carbon nanotube uptake was measured via high-speed confocal Raman imaging in live cells. Spatial and temporal tracking of two cell-intrinsic and nine nanotube-derived Raman bands was conducted simultaneously in RAW 264.7 macrophages. Movies resolved single (n, m) species, defects, and aggregation states of nanotubes transiently as well as the cell position, denoted by lipid and protein signals. This work portends the real-time molecular imaging of live cells and tissues using Raman spectroscopy, affording multiplexing and complete photostability. © 2012 American Chemical Society.
Keywords: molecular probe; intracellular trafficking; raman spectroscopy; raman microscopy; resonance raman scattering; single-walled carbon nanotube
Journal Title: Nano Letters
Volume: 12
Issue: 12
ISSN: 1530-6984
Publisher: American Chemical Society  
Date Published: 2012-12-12
Start Page: 6170
End Page: 6174
Language: English
DOI: 10.1021/nl302991y
PROVIDER: scopus
PUBMED: 23151070
PMCID: PMC3561480
DOI/URL:
Notes: --- - "Export Date: 2 January 2013" - "CODEN: NALEF" - "Source: Scopus"
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  1. Daniel Alan Heller
    103 Heller